Urothelial bladder carcinoma in young patients is characterized by a relatively good prognosis
Abstract Introduction and aim. Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features. Material and methods. Altogeth...
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| Veröffentlicht in: | Upsala journal of medical sciences 2012-03, Vol.117 (1), p.47-51 |
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| creator | Poletajew, S awomir Wal dziak, Maciej Fus, ukasz Pomada, Pawe Ciecha ska, Joanna Wasiuty ski, Aleksander |
| description | Abstract
Introduction and aim.
Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features.
Material and methods.
Altogether 2160 patients treated with primary transurethral resection due to a bladder tumor were included in the study. The mean age of the cohort was 69.1 years (range 11-100). Patients were divided into three subgroups depending on age: age 50 years (group 3). Sex ratio, tumor grade, and stage of disease were recorded.
Results.
Women constituted 18.5%, 19.2%, and 25.8% of the patients in groups 1, 2, and 3, respectively (P < 0.05). WHO grade 3 tumors were diagnosed in 0%, 8.5%, and 17.2%, respectively (P < 0.05). Non-invasive papillary carcinoma was found in 100.0%, 76.7%, and 62.7%, respectively (P < 0.05). The incidence of muscle-invasive bladder cancer was 0%, 11.0%, and 15.6%, respectively (P < 0.05).
Conclusions.
Pathological characteristics of UBC are dependent on the patients' age. Being a very rare condition, UBC in young patients is characterized by a relatively good prognosis. |
| doi_str_mv | 10.3109/03009734.2011.650797 |
| format | Article |
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Introduction and aim.
Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features.
Material and methods.
Altogether 2160 patients treated with primary transurethral resection due to a bladder tumor were included in the study. The mean age of the cohort was 69.1 years (range 11-100). Patients were divided into three subgroups depending on age: age <41 years (group 1), age 41-50 years (group 2), age >50 years (group 3). Sex ratio, tumor grade, and stage of disease were recorded.
Results.
Women constituted 18.5%, 19.2%, and 25.8% of the patients in groups 1, 2, and 3, respectively (P < 0.05). WHO grade 3 tumors were diagnosed in 0%, 8.5%, and 17.2%, respectively (P < 0.05). Non-invasive papillary carcinoma was found in 100.0%, 76.7%, and 62.7%, respectively (P < 0.05). The incidence of muscle-invasive bladder cancer was 0%, 11.0%, and 15.6%, respectively (P < 0.05).
Conclusions.
Pathological characteristics of UBC are dependent on the patients' age. Being a very rare condition, UBC in young patients is characterized by a relatively good prognosis.</description><identifier>ISSN: 0300-9734</identifier><identifier>EISSN: 2000-1967</identifier><identifier>DOI: 10.3109/03009734.2011.650797</identifier><identifier>PMID: 22283443</identifier><language>eng</language><publisher>England: Informa Healthcare</publisher><subject>Adolescent ; Adult ; Age ; Age factors ; age of onset ; Aged ; Aged, 80 and over ; Bladder ; Bladder cancer ; Child ; Cohort Studies ; Female ; histopathology ; Humans ; Male ; Middle Aged ; Original ; prognosis ; Urinary Bladder Neoplasms - pathology ; Young Adult</subject><ispartof>Upsala journal of medical sciences, 2012-03, Vol.117 (1), p.47-51</ispartof><rights>Informa Healthcare 2012</rights><rights>Informa Healthcare. 2012. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0 (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-2514faf3e7403e1915a231c285f3217093dfb83fb11b6aaa2700a34ed6f17fca3</citedby><cites>FETCH-LOGICAL-c500t-2514faf3e7403e1915a231c285f3217093dfb83fb11b6aaa2700a34ed6f17fca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282242/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282242/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27479,27901,27902,53766,53768,59116,59117,61191,61192</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22283443$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Poletajew, S awomir</creatorcontrib><creatorcontrib>Wal dziak, Maciej</creatorcontrib><creatorcontrib>Fus, ukasz</creatorcontrib><creatorcontrib>Pomada, Pawe</creatorcontrib><creatorcontrib>Ciecha ska, Joanna</creatorcontrib><creatorcontrib>Wasiuty ski, Aleksander</creatorcontrib><title>Urothelial bladder carcinoma in young patients is characterized by a relatively good prognosis</title><title>Upsala journal of medical sciences</title><addtitle>Ups J Med Sci</addtitle><description>Abstract
Introduction and aim.
Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features.
Material and methods.
Altogether 2160 patients treated with primary transurethral resection due to a bladder tumor were included in the study. The mean age of the cohort was 69.1 years (range 11-100). Patients were divided into three subgroups depending on age: age <41 years (group 1), age 41-50 years (group 2), age >50 years (group 3). Sex ratio, tumor grade, and stage of disease were recorded.
Results.
Women constituted 18.5%, 19.2%, and 25.8% of the patients in groups 1, 2, and 3, respectively (P < 0.05). WHO grade 3 tumors were diagnosed in 0%, 8.5%, and 17.2%, respectively (P < 0.05). Non-invasive papillary carcinoma was found in 100.0%, 76.7%, and 62.7%, respectively (P < 0.05). The incidence of muscle-invasive bladder cancer was 0%, 11.0%, and 15.6%, respectively (P < 0.05).
Conclusions.
Pathological characteristics of UBC are dependent on the patients' age. Being a very rare condition, UBC in young patients is characterized by a relatively good prognosis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Age factors</subject><subject>age of onset</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Bladder</subject><subject>Bladder cancer</subject><subject>Child</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>histopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original</subject><subject>prognosis</subject><subject>Urinary Bladder Neoplasms - pathology</subject><subject>Young Adult</subject><issn>0300-9734</issn><issn>2000-1967</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kUtv3CAURlHVKplO-w-qCqmLrjzhYZvxJlUU9SVF6qbZFl1jGBNhmIKdyvn1wZo8miyyYnHP_eDjIPSBkg2npDkhnJBG8HLDCKWbuiKiEa_QihFCCtrU4jVaLUixMMfobUpXeVITwY_QMWNsy8uSr9CfyxjGXjsLDrcOuk5HrCAq68MA2Ho8h8nv8B5Gq_2YsE1Y9RBBjTraG93hdsaAo3YZuNZuxrsQOryPYedDsukdemPAJf3-7lyjy29ff5__KC5-ff95fnZRqIqQsWAVLQ0YrkVJuKYNrYBxqti2MpxRQRremXbLTUtpWwMAE4QAL3VXGyqMAr5Gp4fc_dQOulP5rRGc3Ec7QJxlACufTrzt5S5cS862jJUsB3y-C4jh76TTKAeblHYOvA5Tkk3-MlrTaiE_PSOvwhR9bicZbRqWPeQSa1QeKBVDSlGbh7dQIhd_8t6fXPzJg7-89vH_Hg9L98Iy8OUAWG9CHOBfiK6TI8wuRBPBK5uW-BevOH2S0GtwY5-d68ciLwbcApahvpI</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>Poletajew, S awomir</creator><creator>Wal dziak, Maciej</creator><creator>Fus, ukasz</creator><creator>Pomada, Pawe</creator><creator>Ciecha ska, Joanna</creator><creator>Wasiuty ski, Aleksander</creator><general>Informa Healthcare</general><general>Taylor & Francis</general><general>Open Academia</general><scope>0YH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20120301</creationdate><title>Urothelial bladder carcinoma in young patients is characterized by a relatively good prognosis</title><author>Poletajew, S awomir ; Wal dziak, Maciej ; Fus, ukasz ; Pomada, Pawe ; Ciecha ska, Joanna ; Wasiuty ski, Aleksander</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-2514faf3e7403e1915a231c285f3217093dfb83fb11b6aaa2700a34ed6f17fca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Age factors</topic><topic>age of onset</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Bladder</topic><topic>Bladder cancer</topic><topic>Child</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>histopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original</topic><topic>prognosis</topic><topic>Urinary Bladder Neoplasms - pathology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Poletajew, S awomir</creatorcontrib><creatorcontrib>Wal dziak, Maciej</creatorcontrib><creatorcontrib>Fus, ukasz</creatorcontrib><creatorcontrib>Pomada, Pawe</creatorcontrib><creatorcontrib>Ciecha ska, Joanna</creatorcontrib><creatorcontrib>Wasiuty ski, Aleksander</creatorcontrib><collection>Taylor & Francis Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Upsala journal of medical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Poletajew, S awomir</au><au>Wal dziak, Maciej</au><au>Fus, ukasz</au><au>Pomada, Pawe</au><au>Ciecha ska, Joanna</au><au>Wasiuty ski, Aleksander</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Urothelial bladder carcinoma in young patients is characterized by a relatively good prognosis</atitle><jtitle>Upsala journal of medical sciences</jtitle><addtitle>Ups J Med Sci</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>117</volume><issue>1</issue><spage>47</spage><epage>51</epage><pages>47-51</pages><issn>0300-9734</issn><eissn>2000-1967</eissn><abstract>Abstract
Introduction and aim.
Urothelial bladder carcinoma (UBC) is a very rare condition in patients aged below 50 years. The aim of the study was to answer the question whether the characteristics of cancer in this group of patients differ from general UBC features.
Material and methods.
Altogether 2160 patients treated with primary transurethral resection due to a bladder tumor were included in the study. The mean age of the cohort was 69.1 years (range 11-100). Patients were divided into three subgroups depending on age: age <41 years (group 1), age 41-50 years (group 2), age >50 years (group 3). Sex ratio, tumor grade, and stage of disease were recorded.
Results.
Women constituted 18.5%, 19.2%, and 25.8% of the patients in groups 1, 2, and 3, respectively (P < 0.05). WHO grade 3 tumors were diagnosed in 0%, 8.5%, and 17.2%, respectively (P < 0.05). Non-invasive papillary carcinoma was found in 100.0%, 76.7%, and 62.7%, respectively (P < 0.05). The incidence of muscle-invasive bladder cancer was 0%, 11.0%, and 15.6%, respectively (P < 0.05).
Conclusions.
Pathological characteristics of UBC are dependent on the patients' age. Being a very rare condition, UBC in young patients is characterized by a relatively good prognosis.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>22283443</pmid><doi>10.3109/03009734.2011.650797</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Upsala journal of medical sciences, 2012-03, Vol.117 (1), p.47-51 |
| issn | 0300-9734 2000-1967 |
| language | eng |
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| source | Taylor & Francis Open Access; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Adolescent Adult Age Age factors age of onset Aged Aged, 80 and over Bladder Bladder cancer Child Cohort Studies Female histopathology Humans Male Middle Aged Original prognosis Urinary Bladder Neoplasms - pathology Young Adult |
| title | Urothelial bladder carcinoma in young patients is characterized by a relatively good prognosis |
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