The HIV-1 Rev response element: An RNA scaffold that directs the cooperative assembly of a homo-oligomeric ribonucleoprotein complex

The HIV-1 Rev response element (RRE) is a ~350 nucleotide, highly structured, cis-acting RNA element essential for viral replication. It is located in the env coding region of the viral genome and is extremely well conserved across different HIV-1 isolates. It is present on all partially spliced and...

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Veröffentlicht in:	RNA biology 2012-01, Vol.9 (1), p.6-11
Hauptverfasser:	Fernandes, Jason, Jayaraman, Bhargavi, Frankel, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	assembly Base Sequence Binding Binding Sites Biology Bioscience Calcium Cancer Cell Cycle Databases, Genetic export Gene Expression Regulation, Viral Genes, rev HIV HIV-1 - genetics HIV-1 - metabolism HIV-1 - physiology Landes Molecular Sequence Data Multiprotein Complexes - genetics Multiprotein Complexes - metabolism Nucleic Acid Conformation oligomer Organogenesis Proteins Response Elements Rev Ribonucleoproteins - genetics Ribonucleoproteins - metabolism RNA RNA Families RNA, Messenger - genetics RNA, Messenger - metabolism RRE scaffold Sequence Alignment virus Virus Assembly
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