The Effects of Adiponectin and Leptin on Human Endothelial Cell Proliferation: A Live-Cell Study

The effect of adiponectin and leptin on the proliferation of the human microvascular endothelial cell line (HMEC-1) was studied in the absence or presence of fetal bovine serum (FBS). The participation of extracellular signal-regulated kinase (ERK) and phosphatidylinositol 3-kinase/Akt (PI-3K/Akt) p...

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Veröffentlicht in:	Journal of vascular research 2012-01, Vol.49 (2), p.111-122
Hauptverfasser:	Álvarez, Granada, Visitación Bartolomé, M., Miana, María, Jurado-López, Raquel, Martín, Ruben, Zuluaga, Pilar, Martinez-Martinez, Ernesto, Nieto, M. Luisa, Alvarez-Sala, Luis A., Millán, Jesús, Lahera, Vicente, Cachofeiro, Victoria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - pharmacology Biological and medical sciences Cell Line Cell Movement - drug effects Cell Proliferation - drug effects Chromones - pharmacology Endothelium, Vascular - cytology Extracellular Signal-Regulated MAP Kinases - drug effects Flavonoids - pharmacology Fundamental and applied biological sciences. Psychology Humans Leptin - pharmacology Microcirculation Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors Morpholines - pharmacology Phosphatidylinositol 3-Kinases - antagonists & inhibitors Research Paper Vertebrates: cardiovascular system
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