Progressive multifocal leukoencephalopathy following fludarabine treatment in a chronic lymphocytic leukemia patient

Progressive multifocal leukoencephalopathy (PML) is a neurological disease caused by infection of the central nervous system (CNS) with the JC polyomavirus (JCV). JCV is endemic and infects a large proportion (70-90%) of healthy individuals worldwide, but infection is latent. JCV reactivation may oc...

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Veröffentlicht in:	Experimental oncology 2011-12, Vol.33 (4), p.239
Hauptverfasser:	Lejniece, S, Murovska, M, Chapenko, S, Breikša, B, Jaunmuktane, Z, Feldmane, L, Ziediņa, I, Gomez-Roman, J, Garcia-Cabeza, M, Lejnieks, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Brain - pathology Brain - virology DNA, Viral - blood DNA, Viral - genetics Herpesvirus 7, Human - genetics Humans JC Virus - genetics Leukemia, Lymphocytic, Chronic, B-Cell - complications Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy Leukoencephalopathy, Progressive Multifocal - diagnosis Leukoencephalopathy, Progressive Multifocal - etiology Male Middle Aged Vidarabine - adverse effects Vidarabine - analogs & derivatives Vidarabine - therapeutic use
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