Chronic osteomyelitis due to Pseudomonas aeruginosa: treatment with elastomeric infusor in an outpatient setting

Chronic bacterial osteomyelitis requires long-term antibiotic treatment (at least 6-8 weeks). After in-hospital management, patients are usually discharged and treated in outpatient settings. However, when the aetiology is represented by Gram-negative microorganisms, outpatient treatment could be di...

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Veröffentlicht in:Le infezioni in medicina 2011-12, Vol.19 (4), p.257
Hauptverfasser: Carrega, G, Bartolacci, V, Burastero, G, Casalino Finocchio, G, Izzo, M, Ronca, A, Santoriello, L, Tigano, S, Riccio, G
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container_issue 4
container_start_page 257
container_title Le infezioni in medicina
container_volume 19
creator Carrega, G
Bartolacci, V
Burastero, G
Casalino Finocchio, G
Izzo, M
Ronca, A
Santoriello, L
Tigano, S
Riccio, G
description Chronic bacterial osteomyelitis requires long-term antibiotic treatment (at least 6-8 weeks). After in-hospital management, patients are usually discharged and treated in outpatient settings. However, when the aetiology is represented by Gram-negative microorganisms, outpatient treatment could be difficult. Beta-lactam administration by means of an elastomeric infusor may represent an attractive approach. We report two cases of osteomyelitis due to Pseudomonas aeruginosa successfully treated with continuous ceftazidime administration via an elastomeric infusor in outpatient settings. In both cases the patients were free from clinical and laboratory signs of osteomyelitis at the end of treatment and after 12 months follow-up.
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subjects Anti-Bacterial Agents - therapeutic use
Ceftazidime - therapeutic use
Chronic Disease
Diabetes Complications - drug therapy
Diabetes Complications - microbiology
Elastomers
Equipment Design
Follow-Up Studies
Humans
Infusion Pumps
Infusions, Parenteral - methods
Male
Middle Aged
Osteomyelitis - drug therapy
Osteomyelitis - microbiology
Outpatients
Pseudomonas aeruginosa - drug effects
Pseudomonas Infections - complications
Pseudomonas Infections - drug therapy
Risk Factors
Treatment Outcome
title Chronic osteomyelitis due to Pseudomonas aeruginosa: treatment with elastomeric infusor in an outpatient setting
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