Study on the usefulness of haptoglobin used on endoscopic injection sclerotherapy
The effect of heptoglobin (Hp) used on endoscopic injection sclerotherapy (EIS) was evaluated by examining the increase of serum free hemoglobin (FHb) and the changes of renal function. In control group, the increase of serum FHb (ΔFHb) was paralleled with the volume of 5% Ehanolamine Oleate (EO) in...
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| Veröffentlicht in: | Nippon Shokakibyo Gakkai Zasshi 1990, Vol.87(6), pp.1343-1349 |
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| container_title | Nippon Shokakibyo Gakkai Zasshi |
| container_volume | 87 |
| creator | MATSUMOTO, Akio MIYOSHI, Hirofumi TAKADA, Ko HAYASHI, Katsuyoshi ASADA, Shuji HIRATA, Ichiro OHSHIBA, Saburo |
| description | The effect of heptoglobin (Hp) used on endoscopic injection sclerotherapy (EIS) was evaluated by examining the increase of serum free hemoglobin (FHb) and the changes of renal function. In control group, the increase of serum FHb (ΔFHb) was paralleled with the volume of 5% Ehanolamine Oleate (EO) injected intravariceally, and free Hp (FHp) was disappered in this group soon after EIS. On the contrary, in the group treated with Hp, neither the increase of FHb nor decrease of FHp were recognized. The significant increase of urine β2 microglobulin and NAG was recognized in control group. Therefore, if Hp is used at initial EIS, it would be prevented that serum FHb due to intravascular hemolysis increases, consequently the possibility of renal dysfunction. |
| doi_str_mv | 10.11405/nisshoshi1964.87.1343 |
| format | Article |
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In control group, the increase of serum FHb (ΔFHb) was paralleled with the volume of 5% Ehanolamine Oleate (EO) injected intravariceally, and free Hp (FHp) was disappered in this group soon after EIS. On the contrary, in the group treated with Hp, neither the increase of FHb nor decrease of FHp were recognized. The significant increase of urine β2 microglobulin and NAG was recognized in control group. Therefore, if Hp is used at initial EIS, it would be prevented that serum FHb due to intravascular hemolysis increases, consequently the possibility of renal dysfunction.</description><identifier>ISSN: 0446-6586</identifier><identifier>EISSN: 1349-7693</identifier><identifier>DOI: 10.11405/nisshoshi1964.87.1343</identifier><identifier>PMID: 2214258</identifier><language>jpn</language><publisher>Japan: The Japanese Society of Gastroenterology</publisher><subject>Adult ; Aged ; Esophageal and Gastric Varices - therapy ; Ethanolamine oleate (EO) ; Female ; Haptoglobins - administration & dosage ; Haptoglobins - therapeutic use ; Hemoglobins - metabolism ; Humans ; Infusions, Intravenous ; Kidney Diseases - etiology ; Kidney Diseases - prevention & control ; Male ; Middle Aged ; Oleic Acids - adverse effects ; Sclerosing Solutions - adverse effects ; Sclerotherapy</subject><ispartof>Nippon Shokakibyo Gakkai Zasshi, 1990, Vol.87(6), pp.1343-1349</ispartof><rights>The Japanese Society of Gastroenterology</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2214258$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MATSUMOTO, Akio</creatorcontrib><creatorcontrib>MIYOSHI, Hirofumi</creatorcontrib><creatorcontrib>TAKADA, Ko</creatorcontrib><creatorcontrib>HAYASHI, Katsuyoshi</creatorcontrib><creatorcontrib>ASADA, Shuji</creatorcontrib><creatorcontrib>HIRATA, Ichiro</creatorcontrib><creatorcontrib>OHSHIBA, Saburo</creatorcontrib><title>Study on the usefulness of haptoglobin used on endoscopic injection sclerotherapy</title><title>Nippon Shokakibyo Gakkai Zasshi</title><addtitle>Nippon Shokakibyo Gakkai Zasshi</addtitle><description>The effect of heptoglobin (Hp) used on endoscopic injection sclerotherapy (EIS) was evaluated by examining the increase of serum free hemoglobin (FHb) and the changes of renal function. In control group, the increase of serum FHb (ΔFHb) was paralleled with the volume of 5% Ehanolamine Oleate (EO) injected intravariceally, and free Hp (FHp) was disappered in this group soon after EIS. On the contrary, in the group treated with Hp, neither the increase of FHb nor decrease of FHp were recognized. The significant increase of urine β2 microglobulin and NAG was recognized in control group. Therefore, if Hp is used at initial EIS, it would be prevented that serum FHb due to intravascular hemolysis increases, consequently the possibility of renal dysfunction.</description><subject>Adult</subject><subject>Aged</subject><subject>Esophageal and Gastric Varices - therapy</subject><subject>Ethanolamine oleate (EO)</subject><subject>Female</subject><subject>Haptoglobins - administration & dosage</subject><subject>Haptoglobins - therapeutic use</subject><subject>Hemoglobins - metabolism</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Kidney Diseases - etiology</subject><subject>Kidney Diseases - prevention & control</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Oleic Acids - adverse effects</subject><subject>Sclerosing Solutions - adverse effects</subject><subject>Sclerotherapy</subject><issn>0446-6586</issn><issn>1349-7693</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkM1qwzAQhEVpSUOaR2jxCzjVv6xjCf0lUErbs5FkKVZwJGPJh7x9HRICvezAfsMwuwA8ILhCiEL2GHxKbUytR5LTVSVWiFByBeaTyFJwSa7BHFLKS84qfguWKXkNIZRMVoTMwAxjRDGr5uDrO4_NoYihyK0txmTd2AWbUhFd0ao-x20XtQ9H0hxdNjQxmdh7U_iwsyb7aZlMZ4c4BQyqP9yBG6e6ZJdnXYDfl-ef9Vu5-Xx9Xz9tyh2mLJeCWOwYFY443hhhMZMWKiGY4QppoZlDUGlhpqIECqMVprgiUmpGpOUEkgW4P-X2o97bpu4Hv1fDoT6fNvGPE9-lrLb2wtWQ_dS3_vfCuhI1P43jJy8m06qhtoH8AZHTcBM</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>MATSUMOTO, Akio</creator><creator>MIYOSHI, Hirofumi</creator><creator>TAKADA, Ko</creator><creator>HAYASHI, Katsuyoshi</creator><creator>ASADA, Shuji</creator><creator>HIRATA, Ichiro</creator><creator>OHSHIBA, Saburo</creator><general>The Japanese Society of Gastroenterology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>1990</creationdate><title>Study on the usefulness of haptoglobin used on endoscopic injection sclerotherapy</title><author>MATSUMOTO, Akio ; MIYOSHI, Hirofumi ; TAKADA, Ko ; HAYASHI, Katsuyoshi ; ASADA, Shuji ; HIRATA, Ichiro ; OHSHIBA, Saburo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j245t-73e2f547f3f6dc7e259e0a775c6a1b7b5f10ab7c214307cba2428399b539e6303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>1990</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Esophageal and Gastric Varices - therapy</topic><topic>Ethanolamine oleate (EO)</topic><topic>Female</topic><topic>Haptoglobins - administration & dosage</topic><topic>Haptoglobins - therapeutic use</topic><topic>Hemoglobins - metabolism</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Kidney Diseases - etiology</topic><topic>Kidney Diseases - prevention & control</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Oleic Acids - adverse effects</topic><topic>Sclerosing Solutions - adverse effects</topic><topic>Sclerotherapy</topic><toplevel>online_resources</toplevel><creatorcontrib>MATSUMOTO, Akio</creatorcontrib><creatorcontrib>MIYOSHI, Hirofumi</creatorcontrib><creatorcontrib>TAKADA, Ko</creatorcontrib><creatorcontrib>HAYASHI, Katsuyoshi</creatorcontrib><creatorcontrib>ASADA, Shuji</creatorcontrib><creatorcontrib>HIRATA, Ichiro</creatorcontrib><creatorcontrib>OHSHIBA, Saburo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Nippon Shokakibyo Gakkai Zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MATSUMOTO, Akio</au><au>MIYOSHI, Hirofumi</au><au>TAKADA, Ko</au><au>HAYASHI, Katsuyoshi</au><au>ASADA, Shuji</au><au>HIRATA, Ichiro</au><au>OHSHIBA, Saburo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Study on the usefulness of haptoglobin used on endoscopic injection sclerotherapy</atitle><jtitle>Nippon Shokakibyo Gakkai Zasshi</jtitle><addtitle>Nippon Shokakibyo Gakkai Zasshi</addtitle><date>1990</date><risdate>1990</risdate><volume>87</volume><issue>6</issue><spage>1343</spage><epage>1349</epage><pages>1343-1349</pages><issn>0446-6586</issn><eissn>1349-7693</eissn><abstract>The effect of heptoglobin (Hp) used on endoscopic injection sclerotherapy (EIS) was evaluated by examining the increase of serum free hemoglobin (FHb) and the changes of renal function. In control group, the increase of serum FHb (ΔFHb) was paralleled with the volume of 5% Ehanolamine Oleate (EO) injected intravariceally, and free Hp (FHp) was disappered in this group soon after EIS. On the contrary, in the group treated with Hp, neither the increase of FHb nor decrease of FHp were recognized. The significant increase of urine β2 microglobulin and NAG was recognized in control group. Therefore, if Hp is used at initial EIS, it would be prevented that serum FHb due to intravascular hemolysis increases, consequently the possibility of renal dysfunction.</abstract><cop>Japan</cop><pub>The Japanese Society of Gastroenterology</pub><pmid>2214258</pmid><doi>10.11405/nisshoshi1964.87.1343</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0446-6586 |
| ispartof | Nippon Shokakibyo Gakkai Zasshi, 1990, Vol.87(6), pp.1343-1349 |
| issn | 0446-6586 1349-7693 |
| language | jpn |
| recordid | cdi_pubmed_primary_2214258 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Aged Esophageal and Gastric Varices - therapy Ethanolamine oleate (EO) Female Haptoglobins - administration & dosage Haptoglobins - therapeutic use Hemoglobins - metabolism Humans Infusions, Intravenous Kidney Diseases - etiology Kidney Diseases - prevention & control Male Middle Aged Oleic Acids - adverse effects Sclerosing Solutions - adverse effects Sclerotherapy |
| title | Study on the usefulness of haptoglobin used on endoscopic injection sclerotherapy |
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