Synthesis and antidepressant-like activity of selenophenes obtained via iron(III)-PhSeSePh-mediated cyclization of Z-selenoenynes

We present here the synthesis and antidepressant-like action of a series of 2,5-disubstituted-3-(organoseleno)-selenophenes prepared by a novel synthetic route, the FeCl(3)-diorganyl dichalcogenide-mediated intramolecular cyclization of (Z)-chalcogenoenynes. The cyclized products were obtained in go...

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Veröffentlicht in:	Organic & biomolecular chemistry 2012-01, Vol.10 (4), p.798
Hauptverfasser:	Gai, Bibiana M, Stein, André L, Roehrs, Juliano A, Bilheri, Filipe N, Nogueira, Cristina W, Zeni, Gilson
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - chemical synthesis Antidepressive Agents - chemistry Antidepressive Agents - pharmacology Cyclization Ferric Compounds - chemistry Male Mice Motor Activity - drug effects Organoselenium Compounds - chemical synthesis Organoselenium Compounds - chemistry Organoselenium Compounds - pharmacology Swimming
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