Streptococcal toxic shock syndrome or Kawasaki disease? Two case studies of children with group A streptococcal pneumonia empyema

We report 2 cases of children with group A streptococcus pyogenes pleuropneumonia, in one child associated with Kawasaki disease and in the other with streptococcal toxic shock syndrome. These 2 features, with theoretically well-defined clinical and biological criteria, are difficult to differentiat...

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Veröffentlicht in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2011-12, Vol.18 (12), p.1310
Hauptverfasser: Bosland, A, Arlaud, K, Rousset-Rouvière, C, Fouilloux, V, Paut, O, Dubus, J-C, Bosdure, E
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container_issue 12
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container_title Archives de pédiatrie : organe officiel de la Société française de pédiatrie
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creator Bosland, A
Arlaud, K
Rousset-Rouvière, C
Fouilloux, V
Paut, O
Dubus, J-C
Bosdure, E
description We report 2 cases of children with group A streptococcus pyogenes pleuropneumonia, in one child associated with Kawasaki disease and in the other with streptococcal toxic shock syndrome. These 2 features, with theoretically well-defined clinical and biological criteria, are difficult to differentiate in clinical practice, however, likely due to their pathophysiological links. In case of clinical doubt, an echocardiography needs to be performed to search for coronary involvement and treatment including intravenous immunoglobulins, and an antibiotic with an anti-toxin effect such as clindamycin has to be started early.
doi_str_mv 10.1016/j.arcped.2011.09.027
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects Anti-Bacterial Agents - therapeutic use
Child, Preschool
Clindamycin - therapeutic use
Diagnosis, Differential
Drug Therapy, Combination
Empyema, Pleural - drug therapy
Empyema, Pleural - microbiology
Humans
Immunoglobulins, Intravenous - therapeutic use
Immunologic Factors - therapeutic use
Infant
Male
Mucocutaneous Lymph Node Syndrome - complications
Mucocutaneous Lymph Node Syndrome - diagnosis
Mucocutaneous Lymph Node Syndrome - drug therapy
Pneumonia, Pneumococcal - drug therapy
Pneumonia, Pneumococcal - microbiology
Shock, Septic - diagnosis
Shock, Septic - drug therapy
Shock, Septic - microbiology
Shock, Septic - therapy
Streptococcal Infections - complications
Streptococcal Infections - diagnosis
Streptococcal Infections - drug therapy
Streptococcal Infections - therapy
Streptococcus pyogenes - isolation & purification
Streptococcus pyogenes - pathogenicity
Treatment Outcome
title Streptococcal toxic shock syndrome or Kawasaki disease? Two case studies of children with group A streptococcal pneumonia empyema
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