Development and evaluation of chitosan microspheres for tetanus, diphtheria and divalent vaccines: a comparative study of subcutaneous and intranasal administration in mice

Context: There is a need to use the new technologies to induce immunity with minimum number of vaccination sessions to ensure compliance with reducing cost. Objectives: To develop single shot vaccines of tetanus, diphtheria and divalent toxoids microsphere's formulations and to induce their imm...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmaceutical development and technology 2013-09, Vol.18 (5), p.1175-1185
Hauptverfasser:	Hashem, Fahima M., Fahmy, Sahar A., El-Sayed, Aly M., Al-Sawahli, Majid M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Administration, Intranasal - methods Animals Antibodies - immunology Antigens - administration & dosage Antigens - chemistry Antigens - immunology Chemistry, Pharmaceutical - methods Chitosan - administration & dosage Chitosan - chemistry Chitosan - immunology controlled release Diphtheria - immunology Diphtheria Toxoid - administration & dosage Diphtheria Toxoid - chemistry Diphtheria Toxoid - immunology Diphtheria-Tetanus Vaccine - administration & dosage Diphtheria-Tetanus Vaccine - chemistry Diphtheria-Tetanus Vaccine - immunology Drug Delivery Systems - methods immunogenicity in mice Male Mice Microparticles Microspheres Particle Size single shot vaccine Tetanus - immunology Tetanus Toxoid - administration & dosage Tetanus Toxoid - chemistry Tetanus Toxoid - immunology vaccine delivery
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!