Identification of CD133+ Cells in Pituitary Adenomas

Stem-like cells in tumors are capable of self-renewal and pluri-differentiation; they are thought to play important roles in tumor initiation and maintenance. Stem-like cells in malignant glioma express CD133. We examined samples from human pituitary adenoma, a generally benign neoplasm, for CD133 e...

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Veröffentlicht in:	Neuroendocrinology 2011-01, Vol.94 (4), p.302-312
Hauptverfasser:	Yunoue, Shunji, Arita, Kazunori, Kawano, Hiroto, Uchida, Hiroyuki, Tokimura, Hiroshi, Hirano, Hirofumi
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Adenoma - genetics Adenoma - metabolism Antigens, CD - genetics Antigens, CD - metabolism Antigens, CD34 - metabolism Biological and medical sciences Endocrinopathies Endothelial Cells - metabolism Female Fundamental and applied biological sciences. Psychology Glycoproteins - genetics Glycoproteins - metabolism Humans Hypothalamus. Hypophysis. Epiphysis (diseases) Intermediate Filament Proteins - metabolism Male Medical sciences Middle Aged Nerve Tissue Proteins - metabolism Nestin Non tumoral diseases. Target tissue resistance. Benign neoplasms Original Paper Peptides - genetics Peptides - metabolism Pituitary Neoplasms - genetics Pituitary Neoplasms - metabolism Real-Time Polymerase Chain Reaction S100 Proteins - metabolism Stem Cells - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism Vertebrates: endocrinology
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