H NMR study of monocrotaline and its metabolites in human blood

Monocrotaline (MCT) is a naturally occurring hepatotoxic pyrrolizidine alkaloid found in plants. This investigation is aimed at furthering the understanding of the role of blood in mediating the transport of MCT and its reactive metabolites in humans. Reactions of monocrotaline and its metabolites,...

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Veröffentlicht in:	Food and chemical toxicology 2011-11, Vol.49 (11), p.2793-2799
Hauptverfasser:	Yang, Yi-Cheng, Crowder, John, Wardle, Nicholas J, Yang, Li, White, Kenneth N, Wang, Zheng-Tao, Annie Bligh, S.W
Format:	Artikel
Sprache:	eng
Schlagworte:	blood plasma blood proteins erythrocytes Erythrocytes - chemistry hepatotoxicity Humans Magnetic Resonance Spectroscopy metabolites Molecular Structure monocrotaline Monocrotaline - analogs & derivatives Monocrotaline - blood Monocrotaline - chemistry nuclear magnetic resonance spectroscopy polymerization Pyrrolizidine Alkaloids - blood Pyrrolizidine Alkaloids - chemistry retronecine toxicology
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