Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model

In 2009, a novel H1N1 influenza (pH1N1) virus caused the first influenza pandemic in 40 y. The virus was identified as a triple reassortant between avian, swine, and human influenza viruses, highlighting the importance of reassortment in the generation of viruses with pandemic potential. Previously,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2011-07, Vol.108 (29), p.12084-12088
Hauptverfasser:	Kimble, J. Brian, Sorrell, Erin, Shao, Hongxia, Martin, Philip L, Perez, Daniel Roberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals avian influenza Biological Sciences birds Cell Line Disease transmission Dogs droplets Enzyme-Linked Immunosorbent Assay Ferrets Fowl plague Gene expression genes Genetic mutation H9N2 subtype influenza A virus Hemagglutinins, Viral - genetics Hemagglutinins, Viral - metabolism human influenza humans Immunohistochemistry Infections Influenza A virus Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H9N2 Subtype - genetics Mammals Mustela putorius furo Neuraminidase - genetics Neuraminidase - metabolism Orthomyxoviridae Infections - genetics Orthomyxoviridae Infections - transmission pandemic Pandemics Reassortant Viruses - genetics Replication Swine Swine flu Transmission efficiency Viral Proteins - genetics Viral Proteins - metabolism Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!