BAG3 and friends: Co-chaperones in selective autophagy during aging and disease

There is a reciprocal change in the expression of two members of the BAG (Bcl-2-associated athanogen) family, BAG1 and BAG3, during cellular aging and under acute stress ("BAG1-BAG3-switch"). BAG3 was recently described as a mediator of a novel macroautophagy pathway that uses the specific...

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Veröffentlicht in:	Autophagy 2011-07, Vol.7 (7), p.795-798
1. Verfasser:	Behl, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Adaptor Proteins, Signal Transducing - metabolism Aging - metabolism Animals Autophagy Binding Biology Bioscience Calcium Cancer Cell Cycle Disease DNA-Binding Proteins - metabolism Dyneins - metabolism Landes Models, Biological Molecular Chaperones - metabolism Organogenesis Proteasome Endopeptidase Complex - metabolism Proteins Transcription Factors - metabolism Ubiquitination
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