Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells
The RNA interference-mediated gene silencing approach is promising for therapies based on the targeted inhibition of disease-relevant genes. Electropermeabilization is one of the nonviral methods successfully used to transfer siRNA into living cells in vitro and in vivo. Although this approach is ef...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2011-06, Vol.108 (26), p.10443-10447 |
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