Interactions between Dietary Fat Intake and FASN Genetic Variation Influence LDL Peak Particle Diameter

Background: The small, dense LDL phenotype is associated with an increased cardiovascular disease risk. A genome-wide scan performed on the Quebec Family Study (QFS) revealed a quantitative trait locus for LDL peak particle diameter (LDL-PPD) on the 17q21 region. A positional candidate gene – the fa...

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Veröffentlicht in:	Journal of nutrigenetics and nutrigenomics 2011-01, Vol.4 (3), p.137-145
Hauptverfasser:	Dolley, G., Boisclair, M.E., Lamarche, B., Després, J.P., Bouchard, C., Pérusse, L., Vohl, M.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cohort Studies Dietary Fats - administration & dosage Electrophoresis, Polyacrylamide Gel Fatty Acid Synthase, Type I - genetics Female Genetic Variation Humans Lipoproteins, LDL - chemistry Lipoproteins, LDL - metabolism Male Middle Aged Original Paper Particle Size Polymorphism, Single Nucleotide
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