One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates

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Veröffentlicht in:	Journal of Virology 2011-08, Vol.85 (15), p.7582-7593
Hauptverfasser:	DENTON, Paul W, OTHIENO, Florence, WELCH, Brett D, KAY, Michael S, PAYNE, Deborah A, GALLAY, Philippe, APPELLA, Ettore, ESTES, Jacob D, MIN LU, VICTOR GARCIA, J, MARTINEZ-TORRES, Francisco, WEI ZOU, KRISKO, John F, FLEMING, Elisa, ZEIN, Sima, POWELL, Daniel A, WAHL, Angela, YOUN TAE KWAK
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - analogs & derivatives Administration, Topical Animals Base Sequence Biological and medical sciences CD4-Positive T-Lymphocytes - immunology Chimera Disease Models, Animal DNA Primers Drug Evaluation, Preclinical Female Fundamental and applied biological sciences. Psychology HIV Infections - immunology HIV Infections - prevention & control HIV Infections - transmission Humans Mice Microbiology Miscellaneous Organophosphonates - administration & dosage Receptors, CCR5 - immunology Reverse Transcriptase Inhibitors - administration & dosage Tenofovir Vaccines and Antiviral Agents Vagina Virology
Online-Zugang:	Volltext
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