One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates
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| Veröffentlicht in: | Journal of Virology 2011-08, Vol.85 (15), p.7582-7593 |
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| creator | DENTON, Paul W OTHIENO, Florence WELCH, Brett D KAY, Michael S PAYNE, Deborah A GALLAY, Philippe APPELLA, Ettore ESTES, Jacob D MIN LU VICTOR GARCIA, J MARTINEZ-TORRES, Francisco WEI ZOU KRISKO, John F FLEMING, Elisa ZEIN, Sima POWELL, Daniel A WAHL, Angela YOUN TAE KWAK |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.00537-11</identifier><identifier>PMID: 21593172</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Adenine - administration & dosage ; Adenine - analogs & derivatives ; Administration, Topical ; Animals ; Base Sequence ; Biological and medical sciences ; CD4-Positive T-Lymphocytes - immunology ; Chimera ; Disease Models, Animal ; DNA Primers ; Drug Evaluation, Preclinical ; Female ; Fundamental and applied biological sciences. Psychology ; HIV Infections - immunology ; HIV Infections - prevention & control ; HIV Infections - transmission ; Humans ; Mice ; Microbiology ; Miscellaneous ; Organophosphonates - administration & dosage ; Receptors, CCR5 - immunology ; Reverse Transcriptase Inhibitors - administration & dosage ; Tenofovir ; Vaccines and Antiviral Agents ; Vagina ; Virology</subject><ispartof>Journal of Virology, 2011-08, Vol.85 (15), p.7582-7593</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c549t-1006c08782a76d58b19cd1b70afefa18a0ee1df6a4825bd2f979ef9ce3de03b43</citedby><cites>FETCH-LOGICAL-c549t-1006c08782a76d58b19cd1b70afefa18a0ee1df6a4825bd2f979ef9ce3de03b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147928/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147928/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24388393$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21593172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DENTON, Paul W</creatorcontrib><creatorcontrib>OTHIENO, Florence</creatorcontrib><creatorcontrib>WELCH, Brett D</creatorcontrib><creatorcontrib>KAY, Michael S</creatorcontrib><creatorcontrib>PAYNE, Deborah A</creatorcontrib><creatorcontrib>GALLAY, Philippe</creatorcontrib><creatorcontrib>APPELLA, Ettore</creatorcontrib><creatorcontrib>ESTES, Jacob D</creatorcontrib><creatorcontrib>MIN LU</creatorcontrib><creatorcontrib>VICTOR GARCIA, J</creatorcontrib><creatorcontrib>MARTINEZ-TORRES, Francisco</creatorcontrib><creatorcontrib>WEI ZOU</creatorcontrib><creatorcontrib>KRISKO, John F</creatorcontrib><creatorcontrib>FLEMING, Elisa</creatorcontrib><creatorcontrib>ZEIN, Sima</creatorcontrib><creatorcontrib>POWELL, Daniel A</creatorcontrib><creatorcontrib>WAHL, Angela</creatorcontrib><creatorcontrib>YOUN TAE KWAK</creatorcontrib><title>One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21593172</pmid><doi>10.1128/JVI.00537-11</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of Virology, 2011-08, Vol.85 (15), p.7582-7593 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adenine - administration & dosage Adenine - analogs & derivatives Administration, Topical Animals Base Sequence Biological and medical sciences CD4-Positive T-Lymphocytes - immunology Chimera Disease Models, Animal DNA Primers Drug Evaluation, Preclinical Female Fundamental and applied biological sciences. Psychology HIV Infections - immunology HIV Infections - prevention & control HIV Infections - transmission Humans Mice Microbiology Miscellaneous Organophosphonates - administration & dosage Receptors, CCR5 - immunology Reverse Transcriptase Inhibitors - administration & dosage Tenofovir Vaccines and Antiviral Agents Vagina Virology |
| title | One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates |
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