The Effect of Chlorhexidine Varnish on Root Caries: A Systematic Review
Objective: The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries. Materials and Methods: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate stu...
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| Veröffentlicht in: | Caries research 2011-01, Vol.45 (2), p.162-173 |
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| creator | Slot, D.E. Vaandrager, N.C. Van Loveren, C. Van Palenstein Helderman, W.H. Van der Weijden, G.A. |
| description | Objective: The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries. Materials and Methods: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables. Results: An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis. Conclusion: Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as ‘weak’. |
| doi_str_mv | 10.1159/000327374 |
| format | Article |
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Materials and Methods: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables. Results: An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis. Conclusion: Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as ‘weak’.</description><identifier>ISSN: 0008-6568</identifier><identifier>EISSN: 1421-976X</identifier><identifier>DOI: 10.1159/000327374</identifier><identifier>PMID: 21525751</identifier><identifier>CODEN: CAREBK</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Cariostatic Agents - administration & dosage ; Cariostatic Agents - therapeutic use ; Chlorhexidine - administration & dosage ; Chlorhexidine - therapeutic use ; Controlled Clinical Trials as Topic ; Dentistry ; Drug Combinations ; Ethanol - administration & dosage ; Ethanol - therapeutic use ; Gingival Recession - complications ; Humans ; Incidence ; Paint ; Polyurethanes - administration & dosage ; Polyurethanes - therapeutic use ; Review ; Root Caries - drug therapy ; Root Caries - epidemiology ; Root Caries - etiology ; Thymol - administration & dosage ; Thymol - therapeutic use</subject><ispartof>Caries research, 2011-01, Vol.45 (2), p.162-173</ispartof><rights>2011 S. Karger AG, Basel</rights><rights>Copyright © 2011 S. Karger AG, Basel.</rights><rights>Copyright (c) 2011 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-12aaccf46ff031bf2de5ecb2d72719c9a0d7b6cff325bd0c2958ceb20e4fb7e13</citedby><cites>FETCH-LOGICAL-c465t-12aaccf46ff031bf2de5ecb2d72719c9a0d7b6cff325bd0c2958ceb20e4fb7e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21525751$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Slot, D.E.</creatorcontrib><creatorcontrib>Vaandrager, N.C.</creatorcontrib><creatorcontrib>Van Loveren, C.</creatorcontrib><creatorcontrib>Van Palenstein Helderman, W.H.</creatorcontrib><creatorcontrib>Van der Weijden, G.A.</creatorcontrib><title>The Effect of Chlorhexidine Varnish on Root Caries: A Systematic Review</title><title>Caries research</title><addtitle>Caries Res</addtitle><description>Objective: The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries. Materials and Methods: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables. Results: An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis. Conclusion: Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. 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Van Loveren, C. ; Van Palenstein Helderman, W.H. ; Van der Weijden, G.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-12aaccf46ff031bf2de5ecb2d72719c9a0d7b6cff325bd0c2958ceb20e4fb7e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Cariostatic Agents - administration & dosage</topic><topic>Cariostatic Agents - therapeutic use</topic><topic>Chlorhexidine - administration & dosage</topic><topic>Chlorhexidine - therapeutic use</topic><topic>Controlled Clinical Trials as Topic</topic><topic>Dentistry</topic><topic>Drug Combinations</topic><topic>Ethanol - administration & dosage</topic><topic>Ethanol - therapeutic use</topic><topic>Gingival Recession - complications</topic><topic>Humans</topic><topic>Incidence</topic><topic>Paint</topic><topic>Polyurethanes - administration & dosage</topic><topic>Polyurethanes - therapeutic use</topic><topic>Review</topic><topic>Root Caries - drug therapy</topic><topic>Root Caries - epidemiology</topic><topic>Root Caries - etiology</topic><topic>Thymol - administration & dosage</topic><topic>Thymol - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Slot, D.E.</creatorcontrib><creatorcontrib>Vaandrager, N.C.</creatorcontrib><creatorcontrib>Van Loveren, C.</creatorcontrib><creatorcontrib>Van Palenstein Helderman, W.H.</creatorcontrib><creatorcontrib>Van der Weijden, G.A.</creatorcontrib><collection>Karger Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Caries research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Slot, D.E.</au><au>Vaandrager, N.C.</au><au>Van Loveren, C.</au><au>Van Palenstein Helderman, W.H.</au><au>Van der Weijden, G.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Chlorhexidine Varnish on Root Caries: A Systematic Review</atitle><jtitle>Caries research</jtitle><addtitle>Caries Res</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>45</volume><issue>2</issue><spage>162</spage><epage>173</epage><pages>162-173</pages><issn>0008-6568</issn><eissn>1421-976X</eissn><coden>CAREBK</coden><abstract>Objective: The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries. Materials and Methods: The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables. Results: An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis. Conclusion: Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as ‘weak’.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>21525751</pmid><doi>10.1159/000327374</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0008-6568 |
| ispartof | Caries research, 2011-01, Vol.45 (2), p.162-173 |
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| source | Karger Journals; MEDLINE; Alma/SFX Local Collection |
| subjects | Cariostatic Agents - administration & dosage Cariostatic Agents - therapeutic use Chlorhexidine - administration & dosage Chlorhexidine - therapeutic use Controlled Clinical Trials as Topic Dentistry Drug Combinations Ethanol - administration & dosage Ethanol - therapeutic use Gingival Recession - complications Humans Incidence Paint Polyurethanes - administration & dosage Polyurethanes - therapeutic use Review Root Caries - drug therapy Root Caries - epidemiology Root Caries - etiology Thymol - administration & dosage Thymol - therapeutic use |
| title | The Effect of Chlorhexidine Varnish on Root Caries: A Systematic Review |
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