Exendin-4 regulates the expression of the ATP-binding cassette transporter A1 via transcriptional factor PREB in the pancreatic β cell line

Background : PRL regulatory element-binding (PREB) protein is a transcription factor that regulates insulin promoter activity in the rat anterior pituitary. The PREB protein is expressed not only in the anterior pituitary but also in pancreatic β cells. Previously, we have reported that PREB plays a...

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Veröffentlicht in:	Journal of endocrinological investigation 2011-10, Vol.34 (9), p.e268-e274
Hauptverfasser:	Miyai, Y., Murao, K., Imachi, H., Li, J., Nishiuchi, Y., Masugata, H., Iwama, H., Kushida, Y., Ishida, T., Haba, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Cell Line DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Endocrinology Exenatide Genes, Reporter Glucose - metabolism Guanine Nucleotide Exchange Factors - genetics Guanine Nucleotide Exchange Factors - metabolism Insulin - metabolism Insulin Secretion Insulin-Secreting Cells - cytology Insulin-Secreting Cells - drug effects Insulin-Secreting Cells - physiology Medicine Medicine & Public Health Metabolic Diseases Original Articles Peptides - pharmacology Promoter Regions, Genetic Rats RNA, Messenger - metabolism RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic - drug effects Venoms - pharmacology
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