Mandibular osteoma in a case of Gardner's syndrome
Gardner's syndrome is characterized by the triad of intestinal polyposis accompanied by multiple hard- and soft-tissue tumors. Untreated, all patients will develop gastrointestinal cancer by the age of 40. Although incurable, progression can be prevented by close monitoring and prophylactic col...
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Veröffentlicht in: | HNO 2011-05, Vol.59 (5), p.523 |
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creator | Fichter, A M Wolff, K-D Mücke, T |
description | Gardner's syndrome is characterized by the triad of intestinal polyposis accompanied by multiple hard- and soft-tissue tumors. Untreated, all patients will develop gastrointestinal cancer by the age of 40. Although incurable, progression can be prevented by close monitoring and prophylactic colectomy to prevent malignancy. Multiple osteomas of the head and jaw bones are common extraintestinal manifestations of Gardner's syndrome and can be helpful in the diagnostic work-up. The disease pattern should be known to the treating physician, since extraintestinal manifestations usually occur long before intestinal polyposis and early diagnosis is critical for the prognosis. |
doi_str_mv | 10.1007/s00106-011-2316-x |
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Untreated, all patients will develop gastrointestinal cancer by the age of 40. Although incurable, progression can be prevented by close monitoring and prophylactic colectomy to prevent malignancy. Multiple osteomas of the head and jaw bones are common extraintestinal manifestations of Gardner's syndrome and can be helpful in the diagnostic work-up. 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The disease pattern should be known to the treating physician, since extraintestinal manifestations usually occur long before intestinal polyposis and early diagnosis is critical for the prognosis.</description><subject>Adult</subject><subject>Gardner Syndrome - diagnosis</subject><subject>Gardner Syndrome - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Mandibular Neoplasms - diagnosis</subject><subject>Mandibular Neoplasms - surgery</subject><subject>Osteoma - diagnosis</subject><subject>Osteoma - surgery</subject><subject>Treatment Outcome</subject><issn>1433-0458</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1js1KAzEURoMgtlYfwI1k5yp6bzLJJEspWoWKG12Xm8kdGOn8kLRg394BdXW-xeHjCHGDcI8A9UMBQHAKEJU26NT3mVhiZYyCyvqFuCzlazZs0OZCLDRamGe1FPqNhtTF456yHMuBx55kN0iSDRWWYys3lNPA-a7IchpSHnu-Euct7Qtf_3ElPp-fPtYvavu-eV0_btWE4A9KA4dAITofGz83YPI1A4VaV7WzurFoYtJWt7G1CKZh4BRj9Bx8qsk5sxK3v7_TMfacdlPuesqn3X-8-QGqJUPM</recordid><startdate>201105</startdate><enddate>201105</enddate><creator>Fichter, A M</creator><creator>Wolff, K-D</creator><creator>Mücke, T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>201105</creationdate><title>Mandibular osteoma in a case of Gardner's syndrome</title><author>Fichter, A M ; Wolff, K-D ; Mücke, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p108t-20e99a9b68bc84581d87e0a97247652c513bd252fbf5103ce0edbbb8e98d7a663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Gardner Syndrome - diagnosis</topic><topic>Gardner Syndrome - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Mandibular Neoplasms - diagnosis</topic><topic>Mandibular Neoplasms - surgery</topic><topic>Osteoma - diagnosis</topic><topic>Osteoma - surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fichter, A M</creatorcontrib><creatorcontrib>Wolff, K-D</creatorcontrib><creatorcontrib>Mücke, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>HNO</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fichter, A M</au><au>Wolff, K-D</au><au>Mücke, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mandibular osteoma in a case of Gardner's syndrome</atitle><jtitle>HNO</jtitle><addtitle>HNO</addtitle><date>2011-05</date><risdate>2011</risdate><volume>59</volume><issue>5</issue><spage>523</spage><pages>523-</pages><eissn>1433-0458</eissn><abstract>Gardner's syndrome is characterized by the triad of intestinal polyposis accompanied by multiple hard- and soft-tissue tumors. Untreated, all patients will develop gastrointestinal cancer by the age of 40. Although incurable, progression can be prevented by close monitoring and prophylactic colectomy to prevent malignancy. Multiple osteomas of the head and jaw bones are common extraintestinal manifestations of Gardner's syndrome and can be helpful in the diagnostic work-up. The disease pattern should be known to the treating physician, since extraintestinal manifestations usually occur long before intestinal polyposis and early diagnosis is critical for the prognosis.</abstract><cop>Germany</cop><pmid>21505924</pmid><doi>10.1007/s00106-011-2316-x</doi></addata></record> |
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subjects | Adult Gardner Syndrome - diagnosis Gardner Syndrome - surgery Humans Male Mandibular Neoplasms - diagnosis Mandibular Neoplasms - surgery Osteoma - diagnosis Osteoma - surgery Treatment Outcome |
title | Mandibular osteoma in a case of Gardner's syndrome |
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