p27(Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary

Cell cycle inhibitors, such as the cyclin-dependent kinase (Cdk) inhibitor proteins and retinoblastoma (Rb) family members, control exit from the cell cycle during the development of a variety of terminally differentiated tissues. It is unclear whether sustained expression of these proteins is requi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2011-04, Vol.10 (8), p.1237
Hauptverfasser:	Oesterle, Elizabeth C, Chien, Wei-Ming, Campbell, Sean, Nellimarla, Praveena, Fero, Matthew L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Cell Cycle - drug effects Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Differentiation - drug effects Cell Differentiation - genetics Cell Division - drug effects Cell Survival Chickens Cyclin-Dependent Kinase Inhibitor p27 - genetics Cyclin-Dependent Kinase Inhibitor p27 - metabolism Cyclin-Dependent Kinases - antagonists & inhibitors Cyclin-Dependent Kinases - genetics Cyclin-Dependent Kinases - metabolism Cyclins - genetics Cyclins - metabolism Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Humans Mice Mice, Knockout Neoplasms, Experimental - chemically induced Neoplasms, Experimental - genetics Neoplasms, Experimental - metabolism Organ of Corti - cytology Organ of Corti - embryology Organ of Corti - metabolism Organogenesis Pituitary Gland, Intermediate - embryology Pituitary Gland, Intermediate - metabolism Pituitary Gland, Intermediate - pathology Retinoblastoma Protein - genetics Retinoblastoma Protein - metabolism Tamoxifen - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!