Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

O-GlcNAcylation is the addition of β-D- N -acetylglucosamine to serine or threonine residues of nuclear and cytoplasmic proteins. O-linked N -acetylglucosamine (O-GlcNAc) was not discovered until the early 1980s and still remains difficult to detect and quantify. Nonetheless, O-GlcNAc is highly abun...

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