Inhibition of Aβ42 peptide aggregation by a binuclear ruthenium(II)-platinum(II) complex: Potential for multi-metal organometallics as anti-amyloid agents

Design of inhibitors for amyloid-β (Aβ) peptide aggregation has been widely investigated over the years towards developing viable therapeutic agents for Alzheimer's disease (AD). The biggest challenge seems to be inhibiting Aβ aggregation at the early stages of aggregation possibly at the monom...

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Veröffentlicht in:	ACS chemical neuroscience 2010-08, Vol.2010 (10), p.691
Hauptverfasser:	Kumar, Amit, Moody, Lamaryet, Olaivar, Jason F, Lewis, Nerissa A, Khade, Rahul L, Holder, Alvin A, Zhang, Yong, Rangachari, Vijayaraghavan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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