Dysregulation of sphingolipid metabolism in cancer

Altered sphingolipid metabolism contributes to cancer progression and presents an exploitable target for the development of novel chemotherapeutics. Bioactive sphingolipid metabolites also have the potential to serve as vital biomarkers for cancer and be utilized to determine disease progression, as...

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Veröffentlicht in:	Cancer biology & therapy 2011-01, Vol.11 (2), p.138-149
Hauptverfasser:	Ryland, Lindsay K., Fox, Todd E., Liu, Xin, Loughran, Thomas P., Kester, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - metabolism Antineoplastic Agents - therapeutic use Binding Biology Bioscience Calcium Cancer Cell Cycle Forecasting Humans Landes Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - therapy Organogenesis Proteins Sphingolipids - chemistry Sphingolipids - metabolism Sphingolipids - physiology
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