Smaller Hippocampus Volume Is Associated with Short Variant of 5-HTTLPR Polymorphism in Medication-Free Major Depressive Disorder Patients

Aim: Serotonin is known for its importance in the pathophysiology of major depressive disorder. Although the hippocampus is one of the key regions in which neurogenesis occurs, and serotonin plays an important role in neurogenesis, results of studies that investigate effect of the 5-HTTLPR polymorph...

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Veröffentlicht in:	Neuropsychobiology 2011-01, Vol.63 (1), p.22-28
Hauptverfasser:	Eker, M. Cagdas, Kitis, Omer, Okur, Hamza, Eker, Ozlem Donat, Ozan, Erol, Isikli, Serhan, Akarsu, Nurten, Gonul, Ali Saffet
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Depressive Disorder, Major - genetics Depressive Disorder, Major - pathology Female Genotype Hippocampus - pathology Humans Magnetic Resonance Imaging - methods Male Original Paper Polymorphism, Genetic Psychiatric Status Rating Scales Serotonin Plasma Membrane Transport Proteins - genetics
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