On the toxicology of carbromal. II. Pharmacokinetics of carbromal and its hypnotically active metabolites in the rat (author's transl)

Oral doses up to 20 mg/kg of carbromal and of bromoethylbutyramide were rapidly absorbed in the rat. Absorption from the stomach ligated at the pyloric end was 5-8 fold less than absorption of carbromal injected directly into the small intestine. Oral doses greater than 20 mg/kg of carbromal disappe...

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Veröffentlicht in:	Archives of toxicology 1977-08, Vol.37 (4), p.275
Hauptverfasser:	Vohland, H W, Hadisoemarto, S, Wanke, B
Format:	Artikel
Sprache:	eng ; ger
Schlagworte:	Administration, Oral Animals Biotransformation Brain - metabolism Female Gastric Mucosa - metabolism Intestinal Absorption Intestinal Mucosa - metabolism Muscle, Smooth - drug effects Rats Urea - administration & dosage Urea - metabolism Urea - toxicity
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