Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma
Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time. Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postintervention...
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| Veröffentlicht in: | HNO 2010-08, Vol.58 (8), p.853 |
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| creator | Lehmann, M Ulrich, S Reineke, U Hamberger, U Dietrich, U Sudhoff, H |
| description | Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time. Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postinterventional angiography showed complete occlusion of all supporting blood vessels. Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications. Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications. It could represent a new strategy for the treatment of JNA, as is already the case with other highly vascularized head and neck tumors. Moreover, it increases the likelihood of achieving complete resection. |
| doi_str_mv | 10.1007/s00106-010-2146-2 |
| format | Article |
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Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postinterventional angiography showed complete occlusion of all supporting blood vessels. Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications. Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications. It could represent a new strategy for the treatment of JNA, as is already the case with other highly vascularized head and neck tumors. 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Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postinterventional angiography showed complete occlusion of all supporting blood vessels. Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications. Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications. It could represent a new strategy for the treatment of JNA, as is already the case with other highly vascularized head and neck tumors. Moreover, it increases the likelihood of achieving complete resection.</description><subject>Adolescent</subject><subject>Angiofibroma - blood supply</subject><subject>Angiofibroma - diagnosis</subject><subject>Angiofibroma - surgery</subject><subject>Angiography</subject><subject>Dimethyl Sulfoxide</subject><subject>Embolization, Therapeutic - methods</subject><subject>Endoscopy</subject><subject>Humans</subject><subject>Male</subject><subject>Nasopharyngeal Neoplasms - blood supply</subject><subject>Nasopharyngeal Neoplasms - diagnosis</subject><subject>Nasopharyngeal Neoplasms - surgery</subject><subject>Polyvinyls</subject><subject>Postoperative Complications - diagnostic imaging</subject><subject>Preoperative Care</subject><subject>Tomography, X-Ray Computed</subject><issn>1433-0458</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFjrHKwjAURoMg6q8-gIvkBfKbNG3VWRSdXBzc5BZva6S5KUkq-vZ20NnlO8s58DE2U_JfSblcBCmVzEU3IlFpLpIeG6lUayHTbDVkfyHcOyNbJ3rAhonM1nm-0iN2PlD0EFvrPNT8SK8nR1u42gSIxhE3xOMNuQWCCi1S5K7k9_aBZGrkBME1N_AvqrDLgSrjSlN4Z2HC-iXUAacfjtl8tz1t9qJpC4vXS-ON7cLL94r-KbwB-A1FyQ</recordid><startdate>201008</startdate><enddate>201008</enddate><creator>Lehmann, M</creator><creator>Ulrich, S</creator><creator>Reineke, U</creator><creator>Hamberger, U</creator><creator>Dietrich, U</creator><creator>Sudhoff, H</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>201008</creationdate><title>Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma</title><author>Lehmann, M ; Ulrich, S ; Reineke, U ; Hamberger, U ; Dietrich, U ; Sudhoff, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_205966833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Angiofibroma - blood supply</topic><topic>Angiofibroma - diagnosis</topic><topic>Angiofibroma - surgery</topic><topic>Angiography</topic><topic>Dimethyl Sulfoxide</topic><topic>Embolization, Therapeutic - methods</topic><topic>Endoscopy</topic><topic>Humans</topic><topic>Male</topic><topic>Nasopharyngeal Neoplasms - blood supply</topic><topic>Nasopharyngeal Neoplasms - diagnosis</topic><topic>Nasopharyngeal Neoplasms - surgery</topic><topic>Polyvinyls</topic><topic>Postoperative Complications - diagnostic imaging</topic><topic>Preoperative Care</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lehmann, M</creatorcontrib><creatorcontrib>Ulrich, S</creatorcontrib><creatorcontrib>Reineke, U</creatorcontrib><creatorcontrib>Hamberger, U</creatorcontrib><creatorcontrib>Dietrich, U</creatorcontrib><creatorcontrib>Sudhoff, H</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>HNO</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lehmann, M</au><au>Ulrich, S</au><au>Reineke, U</au><au>Hamberger, U</au><au>Dietrich, U</au><au>Sudhoff, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma</atitle><jtitle>HNO</jtitle><addtitle>HNO</addtitle><date>2010-08</date><risdate>2010</risdate><volume>58</volume><issue>8</issue><spage>853</spage><pages>853-</pages><eissn>1433-0458</eissn><abstract>Preoperative embolization for the treatment of juvenile nasopharyngeal angiofibroma was successfully accomplished with Onyx by intratumoral puncture for the first time. Extratumoral migration of Onyx particles was not observed, precluding the necessity to inflate the shield balloon. Postinterventional angiography showed complete occlusion of all supporting blood vessels. Transnasal surgery on the following day achieved complete resection of the angiofibroma without complications. Direct intratumoral embolization of juvenile nasopharyngeal angiofibromas appears to be a safe and effective preoperative method without complications. It could represent a new strategy for the treatment of JNA, as is already the case with other highly vascularized head and neck tumors. Moreover, it increases the likelihood of achieving complete resection.</abstract><cop>Germany</cop><pmid>20596683</pmid><doi>10.1007/s00106-010-2146-2</doi></addata></record> |
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| identifier | EISSN: 1433-0458 |
| ispartof | HNO, 2010-08, Vol.58 (8), p.853 |
| issn | 1433-0458 |
| language | ger |
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| source | MEDLINE; Springer Journals |
| subjects | Adolescent Angiofibroma - blood supply Angiofibroma - diagnosis Angiofibroma - surgery Angiography Dimethyl Sulfoxide Embolization, Therapeutic - methods Endoscopy Humans Male Nasopharyngeal Neoplasms - blood supply Nasopharyngeal Neoplasms - diagnosis Nasopharyngeal Neoplasms - surgery Polyvinyls Postoperative Complications - diagnostic imaging Preoperative Care Tomography, X-Ray Computed |
| title | Intratumoral Onyx embolisation in the management of juvenile nasopharyngeal angiofibroma |
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