Anti-hyperglycaemic effects of the Japanese red maple Acer pycnanthum and its constituents the ginnalins B and C

The anti-hyperglycaemic effects of the leaves of Acer pycnanthum K. Koch, and the purification and identification of the active compounds were investigated. Extracts of the leaves showed a potent inhibitory effect on the α-glucosidase in both in vivo and in vitro experiments. The fractionation of th...

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Veröffentlicht in:	Journal of enzyme inhibition and medicinal chemistry 2011-04, Vol.26 (2), p.176-180
Hauptverfasser:	Honma, Atsushi, Koyama, Tomoyuki, Yazawa, Kazunaga
Format:	Artikel
Sprache:	eng
Schlagworte:	Acer - chemistry Acer pycnanthum Animals diabetes mellitus Enzyme Activation - drug effects Enzyme Inhibitors - pharmacology ginnalin B ginnalin C Hypoglycemic Agents - pharmacology Kinetics Male Mice Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves - chemistry Sorbitol - analogs & derivatives Sorbitol - chemistry Sorbitol - pharmacology Sucrase - antagonists & inhibitors α-glucosidase inhibitory effect
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