DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae

The Saccharomyces cerevisiae DNA polymerase II holoenzyme consists of five polypeptides. The largest is the catalytic subunit, whose gene (POL2) has been cloned and sequenced. Herein we describe the cloning and sequencing of DPB2, the gene for the second largest subunit of DNA polymerase II, and the...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-06, Vol.88 (11), p.4601-4605
Hauptverfasser:	Araki, H. (Osaka University, Suita, Osaka, Japan), Hamatake, R.K, Johnston, L.H, Sugino, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Biochemistry Biological and medical sciences Cell Cycle Cell growth Chromosomes Chromosomes, Fungal CLONACION CLONAGE Cloning, Molecular CODE GENETIQUE CODIGO GENETICO DNA DNA Polymerase II - genetics DNA Polymerase II - isolation & purification DNA Replication DNA-directed DNA polymerase Fundamental and applied biological sciences. Psychology Genes Genes, Fungal Genes. Genome Genetic mutation Genomic Library Hot Temperature Macromolecular Substances Molecular and cellular biology Molecular genetics Molecular Sequence Data MUTANT MUTANTES Mutation NUCLEOTIDE Nucleotide sequences NUCLEOTIDOS PEPTIDE PEPTIDOS Plasmids Restriction Mapping SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - growth & development Transcription, Genetic TRANSFERASAS TRANSFERASE Yeasts
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