Propranolol as a Novel Treatment for Congenital Visceral Haemangioma

Haemangiomas are the most common soft tissue tumours in infancy, occurring in approximately 5–10% of 1-year-old children. Current drug-based therapeutic options for large haemangiomas include corticosteroids, α-interferon and vincristin, all of which can result in harmful side effects. Recently, pro...

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Veröffentlicht in:Neonatology (Basel, Switzerland) Switzerland), 2010-01, Vol.98 (3), p.229-231
Hauptverfasser: Vanlander, Arnaud, Decaluwe, Wim, Vandelanotte, Michel, Van Geet, Christel, Cornette, Luc
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Sprache:eng
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Zusammenfassung:Haemangiomas are the most common soft tissue tumours in infancy, occurring in approximately 5–10% of 1-year-old children. Current drug-based therapeutic options for large haemangiomas include corticosteroids, α-interferon and vincristin, all of which can result in harmful side effects. Recently, promising results have been reported using the non-cardio-selective β-blocker propranolol for the treatment of cutaneous capillary haemangiomas, in which a spectacular size reduction was observed during the first 7 days of treatment. We here report a similar significant and rapid inhibitory effect of propranolol on the growth of a viscerally located congenital haemangioma.
ISSN:1661-7800
1661-7819
DOI:10.1159/000291300