Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study
Purpose: To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies. Methods: IN-ACS (Italian Network on Acute Coronary Syndromes) Outcome, an observational, multicenter study, enrolled 6045 ACS...
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| Veröffentlicht in: | Acute cardiac care 2009, Vol.11 (4), p.222-228 |
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| creator | Pedone, Chiara Di Pasquale, Giuseppe Greco, Cesare Gonzini, Lucio Maggioni, Aldo P. Pavesi, Pier Camillo Sabini, Alessandra Boccanelli, Alessandro On Behalf of IN-ACS Outcome Investigators |
| description | Purpose: To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies. Methods: IN-ACS (Italian Network on Acute Coronary Syndromes) Outcome, an observational, multicenter study, enrolled 6045 ACS patients admitted within 48 h. In the present study we compared the discharge prescription rates of secondary prevention drugs among the 2144 patients with STEMI (72.5% men, age 65±13 years) who received primary percutaneous coronary intervention (pPCI) 1044 (48.7%) or thrombolytic therapy (TT) 575 (26.8%) or no reperfusion treatment (NR) 525 (24.5%). Results: Despite the higher risk profile, NR patients respect to pPCI and TT were less frequently receiving antiplatelet (93.0% versus 99.7% versus 96.4%), dual antiplatelet (57.9% versus 93.9% versus 62.8%), beta-blockers (71.2% versus 82.9 versus 75.0%) and statins (68.4% versus 78.6% versus 76.9%) (P |
| doi_str_mv | 10.1080/17482940903215208 |
| format | Article |
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Results from the IN-ACS outcome study</title><source>MEDLINE</source><source>Taylor & Francis Journals Complete</source><creator>Pedone, Chiara ; Di Pasquale, Giuseppe ; Greco, Cesare ; Gonzini, Lucio ; Maggioni, Aldo P. ; Pavesi, Pier Camillo ; Sabini, Alessandra ; Boccanelli, Alessandro ; On Behalf of IN-ACS Outcome Investigators</creator><creatorcontrib>Pedone, Chiara ; Di Pasquale, Giuseppe ; Greco, Cesare ; Gonzini, Lucio ; Maggioni, Aldo P. ; Pavesi, Pier Camillo ; Sabini, Alessandra ; Boccanelli, Alessandro ; On Behalf of IN-ACS Outcome Investigators ; In-Acs Outcome Investigators</creatorcontrib><description>Purpose: To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies. Methods: IN-ACS (Italian Network on Acute Coronary Syndromes) Outcome, an observational, multicenter study, enrolled 6045 ACS patients admitted within 48 h. In the present study we compared the discharge prescription rates of secondary prevention drugs among the 2144 patients with STEMI (72.5% men, age 65±13 years) who received primary percutaneous coronary intervention (pPCI) 1044 (48.7%) or thrombolytic therapy (TT) 575 (26.8%) or no reperfusion treatment (NR) 525 (24.5%). Results: Despite the higher risk profile, NR patients respect to pPCI and TT were less frequently receiving antiplatelet (93.0% versus 99.7% versus 96.4%), dual antiplatelet (57.9% versus 93.9% versus 62.8%), beta-blockers (71.2% versus 82.9 versus 75.0%) and statins (68.4% versus 78.6% versus 76.9%) (P <0.0001) at discharge. After multivariable analysis, NR respect to pPCI was an independent predictor of not receiving antiplatelet (OR: 19.6; 95% CI: 6.0-62.5), dual antiplatelet (OR: 10.2; 95% CI: 7.6-13.5), beta-blocker (OR: 1.6; 95% CI: 1.3-2.0). Conclusions: According to our results NR patients with STEMI, despite their higher risk profile, were less likely to receive the recommended drugs at discharge compared to patients treated with pPCI.</description><identifier>ISSN: 1748-2941</identifier><identifier>EISSN: 1748-295X</identifier><identifier>DOI: 10.1080/17482940903215208</identifier><identifier>PMID: 19995261</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject><![CDATA[Aged ; Angioplasty, Balloon, Coronary - statistics & numerical data ; Chi-Square Distribution ; Drug Prescriptions - statistics & numerical data ; Drug Utilization ; Female ; Guideline Adherence - statistics & numerical data ; Humans ; Italy - epidemiology ; Logistic Models ; Male ; Middle Aged ; Multicenter Studies as Topic ; Multivariate Analysis ; Myocardial infarction ; Myocardial Infarction - diagnosis ; Myocardial Infarction - epidemiology ; Myocardial Infarction - therapy ; Patient Discharge - statistics & numerical data ; Patient Selection ; Practice Guidelines as Topic ; reperfusion ; Secondary Prevention - organization & administration ; secondary preventive drugs ; Statistics, Nonparametric ; Thrombolytic Therapy - statistics & numerical data ; Treatment Outcome]]></subject><ispartof>Acute cardiac care, 2009, Vol.11 (4), p.222-228</ispartof><rights>2009 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c320t-59a89ae5e178fe8fd9f263953f51d8360effccaf1d24ad6fe93e323e4fe9ef5f3</citedby><cites>FETCH-LOGICAL-c320t-59a89ae5e178fe8fd9f263953f51d8360effccaf1d24ad6fe93e323e4fe9ef5f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/17482940903215208$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/17482940903215208$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,777,781,4010,27904,27905,27906,59626,60415,61200,61381</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19995261$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pedone, Chiara</creatorcontrib><creatorcontrib>Di Pasquale, Giuseppe</creatorcontrib><creatorcontrib>Greco, Cesare</creatorcontrib><creatorcontrib>Gonzini, Lucio</creatorcontrib><creatorcontrib>Maggioni, Aldo P.</creatorcontrib><creatorcontrib>Pavesi, Pier Camillo</creatorcontrib><creatorcontrib>Sabini, Alessandra</creatorcontrib><creatorcontrib>Boccanelli, Alessandro</creatorcontrib><creatorcontrib>On Behalf of IN-ACS Outcome Investigators</creatorcontrib><creatorcontrib>In-Acs Outcome Investigators</creatorcontrib><title>Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study</title><title>Acute cardiac care</title><addtitle>Acute Card Care</addtitle><description>Purpose: To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies. Methods: IN-ACS (Italian Network on Acute Coronary Syndromes) Outcome, an observational, multicenter study, enrolled 6045 ACS patients admitted within 48 h. In the present study we compared the discharge prescription rates of secondary prevention drugs among the 2144 patients with STEMI (72.5% men, age 65±13 years) who received primary percutaneous coronary intervention (pPCI) 1044 (48.7%) or thrombolytic therapy (TT) 575 (26.8%) or no reperfusion treatment (NR) 525 (24.5%). Results: Despite the higher risk profile, NR patients respect to pPCI and TT were less frequently receiving antiplatelet (93.0% versus 99.7% versus 96.4%), dual antiplatelet (57.9% versus 93.9% versus 62.8%), beta-blockers (71.2% versus 82.9 versus 75.0%) and statins (68.4% versus 78.6% versus 76.9%) (P <0.0001) at discharge. After multivariable analysis, NR respect to pPCI was an independent predictor of not receiving antiplatelet (OR: 19.6; 95% CI: 6.0-62.5), dual antiplatelet (OR: 10.2; 95% CI: 7.6-13.5), beta-blocker (OR: 1.6; 95% CI: 1.3-2.0). Conclusions: According to our results NR patients with STEMI, despite their higher risk profile, were less likely to receive the recommended drugs at discharge compared to patients treated with pPCI.</description><subject>Aged</subject><subject>Angioplasty, Balloon, Coronary - statistics & numerical data</subject><subject>Chi-Square Distribution</subject><subject>Drug Prescriptions - statistics & numerical data</subject><subject>Drug Utilization</subject><subject>Female</subject><subject>Guideline Adherence - statistics & numerical data</subject><subject>Humans</subject><subject>Italy - epidemiology</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multicenter Studies as Topic</subject><subject>Multivariate Analysis</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocardial Infarction - therapy</subject><subject>Patient Discharge - statistics & numerical data</subject><subject>Patient Selection</subject><subject>Practice Guidelines as Topic</subject><subject>reperfusion</subject><subject>Secondary Prevention - organization & administration</subject><subject>secondary preventive drugs</subject><subject>Statistics, Nonparametric</subject><subject>Thrombolytic Therapy - statistics & numerical data</subject><subject>Treatment Outcome</subject><issn>1748-2941</issn><issn>1748-295X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFu1DAQhiMEoqXwAFyQb5xS7DjZjQWXalWgUgWIFombNdjjjaskDmOn1T4nL4TTXYEQUk8ejb9_ZvT_RfFS8FPBW_5GrOu2UjVXXFaiqXj7qDheemWlmu-P_9S1OCqexXjDed0ozp8WR0Ip1VQrcVz8-kIYDfkp-TAySMz6aDqgLbLgGKEJw4CjRcsSIaRcp8hcIBbz12iBdmwivM3tRe9HNkHy99CdTx27ui4jbhcVwx5v4Z4adsEAWQ99Fjggs99tTMjNcctSyIsnJDfH5SMmgoRbj_GUfcU498sFFAaWOmQXn8qzzRULc8qXYmZnu3tePHHQR3xxeE-Kb-_Przcfy8vPHy42Z5elkRVPZaOgVYANinXrsHVWuWolVSNdI2wrVxydMwacsFUNduVQSZSVxDpX6BonT4rX-7kThZ8zxqSHbB72PYwY5qjXss4JSMEzKfakoRAjodMT-SGbpwXXS5T6vyiz5tVh-vxjQPtXccguA-_2QDYx0AB3gXqrE-z6QI5gND5q-dD8t__IO4Q-dTkY1DdhpjE798B1vwFLRcZ9</recordid><startdate>2009</startdate><enddate>2009</enddate><creator>Pedone, Chiara</creator><creator>Di Pasquale, Giuseppe</creator><creator>Greco, Cesare</creator><creator>Gonzini, Lucio</creator><creator>Maggioni, Aldo P.</creator><creator>Pavesi, Pier Camillo</creator><creator>Sabini, Alessandra</creator><creator>Boccanelli, Alessandro</creator><creator>On Behalf of IN-ACS Outcome Investigators</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2009</creationdate><title>Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study</title><author>Pedone, Chiara ; Di Pasquale, Giuseppe ; Greco, Cesare ; Gonzini, Lucio ; Maggioni, Aldo P. ; Pavesi, Pier Camillo ; Sabini, Alessandra ; Boccanelli, Alessandro ; On Behalf of IN-ACS Outcome Investigators</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c320t-59a89ae5e178fe8fd9f263953f51d8360effccaf1d24ad6fe93e323e4fe9ef5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Aged</topic><topic>Angioplasty, Balloon, Coronary - statistics & numerical data</topic><topic>Chi-Square Distribution</topic><topic>Drug Prescriptions - statistics & numerical data</topic><topic>Drug Utilization</topic><topic>Female</topic><topic>Guideline Adherence - statistics & numerical data</topic><topic>Humans</topic><topic>Italy - epidemiology</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multicenter Studies as Topic</topic><topic>Multivariate Analysis</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocardial Infarction - therapy</topic><topic>Patient Discharge - statistics & numerical data</topic><topic>Patient Selection</topic><topic>Practice Guidelines as Topic</topic><topic>reperfusion</topic><topic>Secondary Prevention - organization & administration</topic><topic>secondary preventive drugs</topic><topic>Statistics, Nonparametric</topic><topic>Thrombolytic Therapy - statistics & numerical data</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pedone, Chiara</creatorcontrib><creatorcontrib>Di Pasquale, Giuseppe</creatorcontrib><creatorcontrib>Greco, Cesare</creatorcontrib><creatorcontrib>Gonzini, Lucio</creatorcontrib><creatorcontrib>Maggioni, Aldo P.</creatorcontrib><creatorcontrib>Pavesi, Pier Camillo</creatorcontrib><creatorcontrib>Sabini, Alessandra</creatorcontrib><creatorcontrib>Boccanelli, Alessandro</creatorcontrib><creatorcontrib>On Behalf of IN-ACS Outcome Investigators</creatorcontrib><creatorcontrib>In-Acs Outcome Investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acute cardiac care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pedone, Chiara</au><au>Di Pasquale, Giuseppe</au><au>Greco, Cesare</au><au>Gonzini, Lucio</au><au>Maggioni, Aldo P.</au><au>Pavesi, Pier Camillo</au><au>Sabini, Alessandra</au><au>Boccanelli, Alessandro</au><au>On Behalf of IN-ACS Outcome Investigators</au><aucorp>In-Acs Outcome Investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study</atitle><jtitle>Acute cardiac care</jtitle><addtitle>Acute Card Care</addtitle><date>2009</date><risdate>2009</risdate><volume>11</volume><issue>4</issue><spage>222</spage><epage>228</epage><pages>222-228</pages><issn>1748-2941</issn><eissn>1748-295X</eissn><abstract>Purpose: To analyse discharge prescription of recommended treatments in patients with ST-segment elevation myocardial infarction (STEMI) according to reperfusion strategies. Methods: IN-ACS (Italian Network on Acute Coronary Syndromes) Outcome, an observational, multicenter study, enrolled 6045 ACS patients admitted within 48 h. In the present study we compared the discharge prescription rates of secondary prevention drugs among the 2144 patients with STEMI (72.5% men, age 65±13 years) who received primary percutaneous coronary intervention (pPCI) 1044 (48.7%) or thrombolytic therapy (TT) 575 (26.8%) or no reperfusion treatment (NR) 525 (24.5%). Results: Despite the higher risk profile, NR patients respect to pPCI and TT were less frequently receiving antiplatelet (93.0% versus 99.7% versus 96.4%), dual antiplatelet (57.9% versus 93.9% versus 62.8%), beta-blockers (71.2% versus 82.9 versus 75.0%) and statins (68.4% versus 78.6% versus 76.9%) (P <0.0001) at discharge. After multivariable analysis, NR respect to pPCI was an independent predictor of not receiving antiplatelet (OR: 19.6; 95% CI: 6.0-62.5), dual antiplatelet (OR: 10.2; 95% CI: 7.6-13.5), beta-blocker (OR: 1.6; 95% CI: 1.3-2.0). Conclusions: According to our results NR patients with STEMI, despite their higher risk profile, were less likely to receive the recommended drugs at discharge compared to patients treated with pPCI.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>19995261</pmid><doi>10.1080/17482940903215208</doi><tpages>7</tpages></addata></record> |
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| subjects | Aged Angioplasty, Balloon, Coronary - statistics & numerical data Chi-Square Distribution Drug Prescriptions - statistics & numerical data Drug Utilization Female Guideline Adherence - statistics & numerical data Humans Italy - epidemiology Logistic Models Male Middle Aged Multicenter Studies as Topic Multivariate Analysis Myocardial infarction Myocardial Infarction - diagnosis Myocardial Infarction - epidemiology Myocardial Infarction - therapy Patient Discharge - statistics & numerical data Patient Selection Practice Guidelines as Topic reperfusion Secondary Prevention - organization & administration secondary preventive drugs Statistics, Nonparametric Thrombolytic Therapy - statistics & numerical data Treatment Outcome |
| title | Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study |
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