Inhibition of Posthemorrhagic Transfusion-Induced Gastric Injury by a Long-Acting Superoxide Dismutase Derivative

Abstract Although oxygen-free radicals have been postulated to play an important role in the pathogenesis of gastric mucosal injury induced by posthemorrhagic blood transfusion, direct evidence supporting this hypothesis is lacking. Superoxide dismutase (SOD) has been shown to inhibit oxygen toxicit...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1991-02, Vol.196 (2), p.164-169
Hauptverfasser:	Obayashi, Hiroyuki, Koshi, Shuichi, Miyauchi, Yoshimasa, Inoue, Masayasu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Capillary Permeability - drug effects Gastric Mucosa - blood supply Gastric Mucosa - drug effects Gastric Mucosa - injuries Gastroenterology. Liver. Pancreas. Abdomen Heart Rate - drug effects Ischemia - physiopathology Luminescent Measurements Male Maleates - pharmacology Medical sciences Polystyrenes - pharmacology Rats Rats, Inbred Strains Shock, Hemorrhagic - prevention & control Superoxide Dismutase - pharmacology Transfusion Reaction
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