unexpected role for TASK-3 potassium channels in network oscillations with implications for sleep mechanisms and anesthetic action

TASK channels are acid-sensitive and anesthetic-activated members of the family of two-pore-domain potassium channels. We have made the surprising discovery that the genetic ablation of TASK-3 channels eliminates a specific type of theta oscillation in the cortical electroencephalogram (EEG) resembl...

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