Controlled release polymeric ocular delivery of acyclovir

The aim of the present study was to formulate and evaluate controlled release polymeric ocular delivery of acyclovir. Reservoir-type ocular inserts were fabricated by sandwiching hydroxypropyl methylcellulose (HPMC) matrix film containing acyclovir between two rate controlling membranes of cellulose...

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Veröffentlicht in:	Pharmaceutical development and technology 2010-08, Vol.15 (4), p.369-378
Hauptverfasser:	Deshpande, Praful Balavant, Dandagi, Panchaxari, Udupa, Nayanabhirama, Gopal, Shavi V., Jain, Samata S., Vasanth, Surenalli G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir Acyclovir - administration & dosage Acyclovir - chemistry Administration, Topical Animals Antiviral Agents - administration & dosage Antiviral Agents - chemistry beta-Cyclodextrins - chemistry binary systems Cellulose - analogs & derivatives Cellulose - chemistry Delayed-Action Preparations differential scanning calorimetry Diffusion Drug Carriers - chemistry Drug Delivery Systems Drug Stability Drug Storage Gamma Rays Hypromellose Derivatives Male Methylcellulose - analogs & derivatives Methylcellulose - chemistry ocular insert Polymers - chemistry Rabbits Solubility Time Factors β-cyclodextrin
Online-Zugang:	Volltext
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