Optimized Gal4 genetics for permanent gene expression mapping in zebrafish

Combinatorial genetics for conditional transgene activation allows studying gene function with temporal and tissue specific control like the Gal4-UAS system, which has enabled sophisticated genetic studies in DROSOPHILA: Recently this system was adapted for zebrafish and promising applications have...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-08, Vol.106 (32), p.13365-13370
Hauptverfasser:	Distel, Martin, Wullimann, Mario F, Köster, Reinhard W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Brain Cell Nucleus - metabolism Cells Danio rerio DNA-Binding Proteins - genetics Drosophila Embryo, Nonmammalian - cytology Embryo, Nonmammalian - metabolism Embryology Embryos Enhancer Elements, Genetic - genetics Fluorescence Freshwater Gene expression Gene Expression Regulation Genes Genomics Hindbrain Human genetics Medical genetics Messenger RNA Neurons Staining and Labeling Studies Trans-Activators - metabolism Transactivation Transcription Factors - genetics Transgenes Transgenic animals Zebrafish Zebrafish - embryology Zebrafish - genetics Zebrafish Proteins - genetics
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