Sensitive quantification of bulleyaconitine A in human serum by liquid chromatography-tandem mass spectrometry

A simple and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method was developed and validated for the quantification of bulleyaconitine A (BLA) in human serum. Samples were extracted from human serum by protein precipitation. Domperidone was used as internal standard (I.S.). Ch...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2009-07, Vol.73 (7), p.1572-1577
Hauptverfasser:	Xiong, X.(Peking Univ., Beijing (China)), Zhai, S, Yao, Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Aconitine - administration & dosage Aconitine - analogs & derivatives Aconitine - blood Aconitine - chemistry Aconitine - therapeutic use ACONITUM ALCALOIDE ALCALOIDES ALKALOIDS Analgesics - administration & dosage Analgesics - blood Analgesics - chemistry Analgesics - therapeutic use ANALISIS CUANTITATIVO ANALYSE QUANTITATIVE Biological and medical sciences Blood Chemical Analysis - methods BLOOD SERUM bulleyaconitine A Chemical Precipitation Chromatography, Liquid DRUGS ESPECTROMETRIA DE MASAS Fundamental and applied biological sciences. Psychology HPLC human serum Humans Linear Models liquid chromatography-tandem mass spectrometry MASS SPECTROMETRY MEDICAMENT MEDICAMENTOS Osteoarthritis - blood Osteoarthritis - drug therapy Proteins - chemistry QUANTITATIVE ANALYSIS Reproducibility of Results Sensitivity and Specificity SERUM SANGUIN SPECTROMETRIE DE MASSE SUERO SANGUINEO Tandem Mass Spectrometry Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!