Noisy cell growth rate leads to fluctuating protein concentration in bacteria

The present study discusses a prime cause of fluctuating protein concentrations, which play a significant role in generating phenotypic diversity in bacteria. A genetic circuit integrated in a bacterial genome was used to evaluate the cell-to-cell variation in protein concentration. A simple dynamic...

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Veröffentlicht in:	Physical biology 2009-06, Vol.6 (3), p.036015-036015 (9)
Hauptverfasser:	Tsuru, Saburo, Ichinose, Junya, Kashiwagi, Akiko, Ying, Bei-Wen, Kaneko, Kunihiko, Yomo, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes, Bacterial Escherichia coli - chemistry Escherichia coli - genetics Escherichia coli - growth & development Escherichia coli Proteins - analysis Escherichia coli Proteins - genetics Gene Expression Regulation, Bacterial Gene Regulatory Networks Genes, Bacterial Green Fluorescent Proteins - analysis Green Fluorescent Proteins - genetics Models, Biological
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