RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2009-09, Vol.53 (9), p.3952-3962 |
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creator | ALVAREZ, Rene ELBASHIR, Sayda VAN RANST, Mark TRIPP, Ralph A DEVINCENZO, John P PANDEY, Rajendra MAIER, Martin NECHEV, Lubomir MANOHARAN, Muthiah KOTELIANSKI, Victor MEYERS, Rachel BORLAND, Todd TOUDJARSKA, Ivanka HADWIGER, Philipp JOHN, Mathias ROEHL, Ingo SHULGA MORSKAYA, Svetlana MARTINELLO, Rick KAHN, Jeffrey |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.00014-09</identifier><identifier>PMID: 19506055</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Animals ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Antiviral Agents - pharmacology ; Biological and medical sciences ; Cercopithecus aethiops ; Cricetinae ; Female ; Genotype ; Human respiratory syncytial virus ; Human viral diseases ; Humans ; Infectious diseases ; Interferon-alpha - metabolism ; Leukocytes, Mononuclear - drug effects ; Leukocytes, Mononuclear - metabolism ; Medical sciences ; Mice ; Nucleocapsid ; Nucleocapsid - genetics ; Pharmacology. Drug treatments ; Phylogeny ; Respiratory syncytial virus ; Respiratory Syncytial Virus Infections ; Respiratory Syncytial Virus Infections - drug therapy ; Respiratory Syncytial Virus Infections - genetics ; Respiratory Syncytial Virus Infections - virology ; Respiratory Syncytial Virus, Human ; Respiratory Syncytial Virus, Human - classification ; Respiratory Syncytial Virus, Human - drug effects ; Respiratory Syncytial Virus, Human - genetics ; RNA Interference ; RNA Interference - physiology ; RNA, Small Interfering - metabolism ; Tumor Necrosis Factor-alpha - metabolism ; Viral diseases ; Viral diseases of the respiratory system and ent viral diseases</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3952-3962</ispartof><rights>2009 INIST-CNRS</rights><rights>Copyright © 2009 American Society for Microbiology</rights><rights>Copyright © 2009, American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a612t-2f7c3e7a23af4d6ef4a1d22f08d3cc34d53fe865f2041a5957885e4112efec443</citedby><cites>FETCH-LOGICAL-a612t-2f7c3e7a23af4d6ef4a1d22f08d3cc34d53fe865f2041a5957885e4112efec443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737834/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737834/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21845549$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19506055$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ALVAREZ, Rene</creatorcontrib><creatorcontrib>ELBASHIR, Sayda</creatorcontrib><creatorcontrib>VAN RANST, Mark</creatorcontrib><creatorcontrib>TRIPP, Ralph A</creatorcontrib><creatorcontrib>DEVINCENZO, John P</creatorcontrib><creatorcontrib>PANDEY, Rajendra</creatorcontrib><creatorcontrib>MAIER, Martin</creatorcontrib><creatorcontrib>NECHEV, Lubomir</creatorcontrib><creatorcontrib>MANOHARAN, Muthiah</creatorcontrib><creatorcontrib>KOTELIANSKI, Victor</creatorcontrib><creatorcontrib>MEYERS, Rachel</creatorcontrib><creatorcontrib>BORLAND, Todd</creatorcontrib><creatorcontrib>TOUDJARSKA, Ivanka</creatorcontrib><creatorcontrib>HADWIGER, Philipp</creatorcontrib><creatorcontrib>JOHN, Mathias</creatorcontrib><creatorcontrib>ROEHL, Ingo</creatorcontrib><creatorcontrib>SHULGA MORSKAYA, Svetlana</creatorcontrib><creatorcontrib>MARTINELLO, Rick</creatorcontrib><creatorcontrib>KAHN, Jeffrey</creatorcontrib><title>RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Antiviral Agents - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Cercopithecus aethiops</subject><subject>Cricetinae</subject><subject>Female</subject><subject>Genotype</subject><subject>Human respiratory syncytial virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Interferon-alpha - metabolism</subject><subject>Leukocytes, Mononuclear - drug effects</subject><subject>Leukocytes, Mononuclear - metabolism</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Nucleocapsid</subject><subject>Nucleocapsid - genetics</subject><subject>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>19506055</pmid><doi>10.1128/aac.00014-09</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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ispartof | Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3952-3962 |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - pharmacology Biological and medical sciences Cercopithecus aethiops Cricetinae Female Genotype Human respiratory syncytial virus Human viral diseases Humans Infectious diseases Interferon-alpha - metabolism Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Medical sciences Mice Nucleocapsid Nucleocapsid - genetics Pharmacology. Drug treatments Phylogeny Respiratory syncytial virus Respiratory Syncytial Virus Infections Respiratory Syncytial Virus Infections - drug therapy Respiratory Syncytial Virus Infections - genetics Respiratory Syncytial Virus Infections - virology Respiratory Syncytial Virus, Human Respiratory Syncytial Virus, Human - classification Respiratory Syncytial Virus, Human - drug effects Respiratory Syncytial Virus, Human - genetics RNA Interference RNA Interference - physiology RNA, Small Interfering - metabolism Tumor Necrosis Factor-alpha - metabolism Viral diseases Viral diseases of the respiratory system and ent viral diseases |
title | RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy |
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