Chlorpromazine-induced agranulocytosis: a case report

We report the case of a 50-year-old man, treated with chlorpromazine for schizophrenia, who developed an agranulocytosis. Three mechanisms of drugs-induced agranulocytosis have been reported: toxic, genetic and immune. Phenothiazines are responsible for drug-induced agranulocytosis. This patient had...

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Veröffentlicht in:	Encéphale 2009-04, Vol.35 (2), p.173
Hauptverfasser:	Stephan, F, Podlipski, M-A, Kerleau, J-M, Petit, M, Guillin, O
Format:	Artikel
Sprache:	fre
Schlagworte:	Agranulocytosis - chemically induced Agranulocytosis - diagnosis Antipsychotic Agents - adverse effects Antipsychotic Agents - therapeutic use Chlorpromazine - adverse effects Chlorpromazine - therapeutic use Dose-Response Relationship, Drug Drug Interactions Drug Therapy, Combination Humans Leukocyte Count Male Middle Aged Schizophrenia, Paranoid - diagnosis Schizophrenia, Paranoid - drug therapy Schizophrenia, Paranoid - psychology
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