Effect of moxonidine on the uveoscleral outflow: role of alpha2-adrenoceptors or i1 imidazoline receptors

The purpose of this study is to assess the change of uveoscleral outflow induced by moxonidine and to investigate whether the increase of uveoscleral outflow induced by moxonidine is mediated by alpha1, alpha2, or I1 receptors. 0.05% moxonidine was topically and unilaterally administered in rabbit e...

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Veröffentlicht in:	Current eye research 2009-04, Vol.34 (4), p.287
Hauptverfasser:	Yang, Jiangang, Sun, Naixue, Xiong, Quanchen, Yang, Rui
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adrenergic alpha-Antagonists - pharmacology Animals Aqueous Humor - drug effects Aqueous Humor - metabolism Benzofurans - pharmacology Bridged Bicyclo Compounds - pharmacology Drug Synergism Fluorescein-5-isothiocyanate - analogs & derivatives Heptanes - pharmacology Imidazoles - administration & dosage Imidazoles - pharmacology Imidazoline Receptors - antagonists & inhibitors Imidazoline Receptors - metabolism Prazosin - pharmacology Rabbits Receptors, Adrenergic, alpha-2 - metabolism Sclera - drug effects Sclera - metabolism Serum Albumin, Bovine Uvea - drug effects Uvea - metabolism Yohimbine - pharmacology
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