Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in Arabidopsis

The nonsense-mediated mRNA decay (NMD) pathway is a well-known eukaryotic surveillance mechanism that eliminates aberrant mRNAs that contain a premature termination codon (PTC). The UP-Frameshift (UPF) proteins, UPF1, UPF2, and UPF3, are essential for normal NMD function. Several NMD substrates have...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-02, Vol.106 (7), p.2453-2458
Hauptverfasser:	Kurihara, Yukio, Matsui, Akihiro, Hanada, Kousuke, Kawashima, Makiko, Ishida, Junko, Morosawa, Taeko, Tanaka, Maho, Kaminuma, Eli, Mochizuki, Yoshiki, Matsushima, Akihiro, Toyoda, Tetsuro, Shinozaki, Kazuo, Seki, Motoaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense RNA Arabidopsis Arabidopsis - genetics Arabidopsis Proteins - metabolism Arabidopsis thaliana Biochemistry Biological Sciences Cycloheximide - pharmacology degradation Eukaryotes Exons Flowers & plants gene expression regulation Gene Expression Regulation, Plant Genes Genes, Plant genome Genome, Plant Genomes Genomics Introns Messenger RNA microarray technology Models, Biological Models, Genetic Mutation non-coding RNA noncoding RNA Nonsense mutation nonsense-mediated mRNA decay Open reading frames Plant cells premature termination codon Protein Synthesis Inhibitors - pharmacology Proteins Reverse Transcriptase Polymerase Chain Reaction Ribonucleic acid RNA RNA - metabolism RNA stability RNA, Messenger - metabolism RNA, Untranslated - genetics Stop codon tiling array UP-Frameshift proteins
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