Effects of Neonatal Administration of Diethylstilbestrol on Aberrant Crypt Foci Induced by 7,12-Dimethylbenz[Î±]anthracene in Rats

Gastrointestinal carcinoma is affected environmental factors, however, it remains to be determined whether neonatal administration of an estrogenic endocrine disruptor, such as diethylstilbestrol (DES), affects gastrointestinal carcinogenesis. The effects of neonatally administered DES on gastrointe...

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Veröffentlicht in:	In vivo (Athens) 2008-11, Vol.22 (6), p.699
Hauptverfasser:	Kawashima, Hideo, Kawaguchi, Hiroaki, Umekita, Yoshihisa, Souda, Masakazu, Gejima, Kentaro, Komokata, Teruo, Sakata, Ryuzo, Yoshida, Hiroki
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene - administration & dosage 9,10-Dimethyl-1,2-benzanthracene - toxicity Animals Animals, Newborn Atrophy Carcinogens - administration & dosage Carcinogens - toxicity Colon - drug effects Colon - pathology Diethylstilbestrol - pharmacology Dose-Response Relationship, Drug Female Gastrointestinal Neoplasms - chemically induced Gastrointestinal Neoplasms - pathology Intubation, Gastrointestinal Male Rats Rats, Sprague-Dawley Rectum - drug effects Rectum - pathology Sperm Count Testis - abnormalities Testis - drug effects Testis - pathology Weaning
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