Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis

Departments of 1 Medical Research and 6 Ophthalmology, Mackay Memorial Hospital; 2 Department of Microbiology, School of Medicine, National Taiwan University; 3 Department of Ophthalmology and 4 School of Medicine, Taipei Medical University; and 5 Department of Microbiology and Immunology, The Natio...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2009-02, Vol.296 (2), p.C273
Hauptverfasser:	Ho, Tsung-Chuan, Chen, Show-Li, Yang, Yuh-Cheng, Lo, Tzu-Hsiu, Hsieh, Jui-Wen, Cheng, Huey-Chuan, Tsao, Yeou-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Animals Apoptosis - drug effects Arachidonic Acid - metabolism Burns, Chemical - enzymology Burns, Chemical - pathology Caspase 3 - metabolism Cells, Cultured Corneal Neovascularization - enzymology Corneal Neovascularization - pathology Disease Models, Animal Endothelial Cells - drug effects Endothelial Cells - enzymology Endothelial Cells - pathology Eye Burns - chemically induced Eye Burns - enzymology Eye Burns - pathology Eye Proteins - administration & dosage Eye Proteins - metabolism Group IV Phospholipases A2 - antagonists & inhibitors Group IV Phospholipases A2 - genetics Group IV Phospholipases A2 - metabolism Humans Mice Mice, Inbred BALB C Nerve Growth Factors - administration & dosage Nerve Growth Factors - metabolism p38 Mitogen-Activated Protein Kinases - metabolism Phosphodiesterase Inhibitors - pharmacology Phosphorylation PPAR gamma - metabolism Protein Kinase Inhibitors - pharmacology Recombinant Proteins - metabolism RNA Interference Serine Serpins - administration & dosage Serpins - metabolism Signal Transduction - drug effects Time Factors Tumor Suppressor Protein p53 - metabolism
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