Selective delivery of folate-PEG-linked, nanoemulsion-loaded aclacinomycin A to KB nasopharyngeal cells and xenograft: Effect of chain length and amount of folate-PEG linker

To investigate the use of folate-targeted nanoemulsion-loaded aclacinomycin A (ACM) to folate receptor (FR)-positive cells, we attempted to optimize the targeting ability of nanoemulsions by modifying the chain length and amount of the folate-PEG linker. Folate-linked, nanoemulsion-loaded ACM were f...

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Veröffentlicht in:Journal of drug targeting 2008-01, Vol.16 (9), p.660-667
Hauptverfasser: Ohguchi, Yukino, Kawano, Kumi, Hattori, Yoshiyuki, Maitani, Yoshie
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Sprache:eng
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