Calcineurin‐inhibitor minimization protocols in heart transplantation

Summary Cardiac transplantation has become an established method for end‐stage heart disease. A calcineurin‐inhibitor (CNI)‐based regimen is the cornerstone of immunosuppressive therapy after cardiac transplantation. CNIs have reduced acute rejection and infection and markedly increased survival of...

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Veröffentlicht in:	Transplant international 2009-01, Vol.22 (1), p.78-89
Hauptverfasser:	Zuckermann, Andreas Oliver, Aliabadi, Arezu Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcineurin Inhibitors cardiac transplantation Clinical Trials as Topic Drug Administration Schedule Everolimus Graft Rejection - prevention & control Heart Transplantation - immunology Heart Transplantation - methods Humans immunosuppression Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Kidney Failure, Chronic - chemically induced minimization mycophenolate mofetil Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use rapamycin renal dysfunction Sirolimus - analogs & derivatives Sirolimus - therapeutic use
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