Prognostic factors of peripheral T-cell lymphoma (PTL): statistical analysis on 30 patients
Peripheral T-cell lymphoma (PTL) is a distinctive clinical entity, albeit it comprises several diseases with histologically heterogeneous diagnoses. We studied prognostic factors on 30 patients diagnosed and treated at Shikoku Cancer Center Hospital. Clinical findings and laboratory data were evalua...
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| Veröffentlicht in: | Acta medica Okayama 1991-06, Vol.45 (3), p.171 |
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| creator | Toki, H Okabe, K Matsutomo, S Takaba, S Moriwaki, S Motoi, M |
| description | Peripheral T-cell lymphoma (PTL) is a distinctive clinical entity, albeit it comprises several diseases with histologically heterogeneous diagnoses. We studied prognostic factors on 30 patients diagnosed and treated at Shikoku Cancer Center Hospital. Clinical findings and laboratory data were evaluated by statistical analysis to investigate the important factors influencing survival duration. Variables influencing survival were stage, leukemic change, bone marrow infiltration (BMI), anti-human T-lymphocyte virus-type I antibody, white blood cell count, and lactate dehydrogenase (LDH). Multivariate analysis revealed high level of LDH and positive BMI as the important factors for short survival. Histological classifications of the Working Formulation and the T-lymphoma classification by Suchi et al. were also evaluated whether these were related with prognosis. Our data revealed that there was no significant relationship between histological subtype and survival duration. The study of prognostic factors provides valuable aids for us to understand the clinical characteristics of PTL patients with various backgrounds. |
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We studied prognostic factors on 30 patients diagnosed and treated at Shikoku Cancer Center Hospital. Clinical findings and laboratory data were evaluated by statistical analysis to investigate the important factors influencing survival duration. Variables influencing survival were stage, leukemic change, bone marrow infiltration (BMI), anti-human T-lymphocyte virus-type I antibody, white blood cell count, and lactate dehydrogenase (LDH). Multivariate analysis revealed high level of LDH and positive BMI as the important factors for short survival. Histological classifications of the Working Formulation and the T-lymphoma classification by Suchi et al. were also evaluated whether these were related with prognosis. Our data revealed that there was no significant relationship between histological subtype and survival duration. 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The study of prognostic factors provides valuable aids for us to understand the clinical characteristics of PTL patients with various backgrounds.</description><subject>Adult</subject><subject>Aged</subject><subject>Bone Marrow - pathology</subject><subject>Female</subject><subject>HTLV-I Antibodies - analysis</subject><subject>Humans</subject><subject>L-Lactate Dehydrogenase - metabolism</subject><subject>Leukemia - pathology</subject><subject>Leukocyte Count</subject><subject>Lymphoma, T-Cell - mortality</subject><subject>Lymphoma, T-Cell - pathology</subject><subject>Lymphoma, T-Cell - physiopathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Prognosis</subject><subject>Survival Analysis</subject><issn>0386-300X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj81KxDAYRbNQxnH0EYQsdVHIT9Mk7mTwDwrOooLgYvjafnEqaRuSuJi3t-Ks7uLec-GckTWTpiokYx8X5DKlb8ZEaSu2IituLLe6WpPPXZy_pjnloaMOujzHRGdHA8YhHDCCp03RoffUH8dwmEegt7umvrunKUMe_rBlAhP4YxoWcqKS0bA0OOV0Rc4d-ITXp9yQ96fHZvtS1G_Pr9uHupgEt7nQndGi18r0onRWMK60atFBzxWgslpoibw32EoBpeOoFW-xFBYXMSNkKTfk5v83_LQj9vsQhxHicX-SlL-hGkyy</recordid><startdate>19910601</startdate><enddate>19910601</enddate><creator>Toki, H</creator><creator>Okabe, K</creator><creator>Matsutomo, S</creator><creator>Takaba, S</creator><creator>Moriwaki, S</creator><creator>Motoi, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>19910601</creationdate><title>Prognostic factors of peripheral T-cell lymphoma (PTL): statistical analysis on 30 patients</title><author>Toki, H ; Okabe, K ; Matsutomo, S ; Takaba, S ; Moriwaki, S ; Motoi, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-n219t-7c872d758d24f9201575befad15ae597273e1d8eb32a4f1e751be429e30082343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Bone Marrow - pathology</topic><topic>Female</topic><topic>HTLV-I Antibodies - analysis</topic><topic>Humans</topic><topic>L-Lactate Dehydrogenase - metabolism</topic><topic>Leukemia - pathology</topic><topic>Leukocyte Count</topic><topic>Lymphoma, T-Cell - mortality</topic><topic>Lymphoma, T-Cell - pathology</topic><topic>Lymphoma, T-Cell - physiopathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Prognosis</topic><topic>Survival Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Toki, H</creatorcontrib><creatorcontrib>Okabe, K</creatorcontrib><creatorcontrib>Matsutomo, S</creatorcontrib><creatorcontrib>Takaba, S</creatorcontrib><creatorcontrib>Moriwaki, S</creatorcontrib><creatorcontrib>Motoi, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Acta medica Okayama</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Toki, H</au><au>Okabe, K</au><au>Matsutomo, S</au><au>Takaba, S</au><au>Moriwaki, S</au><au>Motoi, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic factors of peripheral T-cell lymphoma (PTL): statistical analysis on 30 patients</atitle><jtitle>Acta medica Okayama</jtitle><addtitle>Acta Med Okayama</addtitle><date>1991-06-01</date><risdate>1991</risdate><volume>45</volume><issue>3</issue><spage>171</spage><pages>171-</pages><issn>0386-300X</issn><abstract>Peripheral T-cell lymphoma (PTL) is a distinctive clinical entity, albeit it comprises several diseases with histologically heterogeneous diagnoses. 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| ispartof | Acta medica Okayama, 1991-06, Vol.45 (3), p.171 |
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| language | eng |
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| source | MEDLINE; Freely Accessible Japanese Titles; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Aged Bone Marrow - pathology Female HTLV-I Antibodies - analysis Humans L-Lactate Dehydrogenase - metabolism Leukemia - pathology Leukocyte Count Lymphoma, T-Cell - mortality Lymphoma, T-Cell - pathology Lymphoma, T-Cell - physiopathology Male Middle Aged Multivariate Analysis Prognosis Survival Analysis |
| title | Prognostic factors of peripheral T-cell lymphoma (PTL): statistical analysis on 30 patients |
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