Star fruit (Averrhoa carambola) toxic encephalopathy

Ingestion of star fruit (Averrhoa carambola) can induce severe intoxication in subjects with chronic renal failure. Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after inge...

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Veröffentlicht in:Revue neurologique 2009-03, Vol.165 (3), p.268
Hauptverfasser: Signaté, A, Olindo, S, Chausson, N, Cassinoto, C, Edimo Nana, M, Saint Vil, M, Cabre, P, Smadja, D
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container_issue 3
container_start_page 268
container_title Revue neurologique
container_volume 165
creator Signaté, A
Olindo, S
Chausson, N
Cassinoto, C
Edimo Nana, M
Saint Vil, M
Cabre, P
Smadja, D
description Ingestion of star fruit (Averrhoa carambola) can induce severe intoxication in subjects with chronic renal failure. Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after ingestion of star fruit. The two patients developed intractable hiccups, vomiting, impaired consciousness and status epilepticus. Diffusion-weighted MR imaging showed cortical and thalamic hyperintense lesions related to epileptic status. They improved after being submitted to continuous hemofiltration which constitutes the most effective treatment during the acute phase.
doi_str_mv 10.1016/j.neurol.2008.06.011
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subjects Aged
Aged, 80 and over
Brain Diseases - chemically induced
Brain Diseases - pathology
Brain Diseases - therapy
Consciousness Disorders - chemically induced
Fruit - adverse effects
Glasgow Coma Scale
Hemofiltration
Hiccup - chemically induced
Humans
Kidney Failure, Chronic - complications
Magnetic Resonance Imaging
Male
Plant Poisoning - pathology
Plant Poisoning - psychology
Plant Poisoning - therapy
Status Epilepticus - chemically induced
Tomography, X-Ray Computed
Vomiting - chemically induced
title Star fruit (Averrhoa carambola) toxic encephalopathy
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