Star fruit (Averrhoa carambola) toxic encephalopathy
Ingestion of star fruit (Averrhoa carambola) can induce severe intoxication in subjects with chronic renal failure. Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after inge...
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Veröffentlicht in: | Revue neurologique 2009-03, Vol.165 (3), p.268 |
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description | Ingestion of star fruit (Averrhoa carambola) can induce severe intoxication in subjects with chronic renal failure. Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after ingestion of star fruit. The two patients developed intractable hiccups, vomiting, impaired consciousness and status epilepticus. Diffusion-weighted MR imaging showed cortical and thalamic hyperintense lesions related to epileptic status. They improved after being submitted to continuous hemofiltration which constitutes the most effective treatment during the acute phase. |
doi_str_mv | 10.1016/j.neurol.2008.06.011 |
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Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after ingestion of star fruit. The two patients developed intractable hiccups, vomiting, impaired consciousness and status epilepticus. Diffusion-weighted MR imaging showed cortical and thalamic hyperintense lesions related to epileptic status. They improved after being submitted to continuous hemofiltration which constitutes the most effective treatment during the acute phase.</description><identifier>ISSN: 0035-3787</identifier><identifier>DOI: 10.1016/j.neurol.2008.06.011</identifier><identifier>PMID: 18755486</identifier><language>fre</language><publisher>France</publisher><subject>Aged ; Aged, 80 and over ; Brain Diseases - chemically induced ; Brain Diseases - pathology ; Brain Diseases - therapy ; Consciousness Disorders - chemically induced ; Fruit - adverse effects ; Glasgow Coma Scale ; Hemofiltration ; Hiccup - chemically induced ; Humans ; Kidney Failure, Chronic - complications ; Magnetic Resonance Imaging ; Male ; Plant Poisoning - pathology ; Plant Poisoning - psychology ; Plant Poisoning - therapy ; Status Epilepticus - chemically induced ; Tomography, X-Ray Computed ; Vomiting - chemically induced</subject><ispartof>Revue neurologique, 2009-03, Vol.165 (3), p.268</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18755486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Signaté, A</creatorcontrib><creatorcontrib>Olindo, S</creatorcontrib><creatorcontrib>Chausson, N</creatorcontrib><creatorcontrib>Cassinoto, C</creatorcontrib><creatorcontrib>Edimo Nana, M</creatorcontrib><creatorcontrib>Saint Vil, M</creatorcontrib><creatorcontrib>Cabre, P</creatorcontrib><creatorcontrib>Smadja, D</creatorcontrib><title>Star fruit (Averrhoa carambola) toxic encephalopathy</title><title>Revue neurologique</title><addtitle>Rev Neurol (Paris)</addtitle><description>Ingestion of star fruit (Averrhoa carambola) can induce severe intoxication in subjects with chronic renal failure. Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after ingestion of star fruit. The two patients developed intractable hiccups, vomiting, impaired consciousness and status epilepticus. Diffusion-weighted MR imaging showed cortical and thalamic hyperintense lesions related to epileptic status. 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Oxalate plays a key role in the neurotoxicity of star fruit. We report the cases of two patients with unknown chronic renal insufficiency who developed severe encephalopathy after ingestion of star fruit. The two patients developed intractable hiccups, vomiting, impaired consciousness and status epilepticus. Diffusion-weighted MR imaging showed cortical and thalamic hyperintense lesions related to epileptic status. They improved after being submitted to continuous hemofiltration which constitutes the most effective treatment during the acute phase.</abstract><cop>France</cop><pmid>18755486</pmid><doi>10.1016/j.neurol.2008.06.011</doi></addata></record> |
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subjects | Aged Aged, 80 and over Brain Diseases - chemically induced Brain Diseases - pathology Brain Diseases - therapy Consciousness Disorders - chemically induced Fruit - adverse effects Glasgow Coma Scale Hemofiltration Hiccup - chemically induced Humans Kidney Failure, Chronic - complications Magnetic Resonance Imaging Male Plant Poisoning - pathology Plant Poisoning - psychology Plant Poisoning - therapy Status Epilepticus - chemically induced Tomography, X-Ray Computed Vomiting - chemically induced |
title | Star fruit (Averrhoa carambola) toxic encephalopathy |
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