Mitochondrial Oxidative Phosphorylation Is Regulated by Fructose 1,6-Bisphosphate: A POSSIBLE ROLE IN CRABTREE EFFECT INDUCTION?

In numerous cell types, tumoral cells, proliferating cells, bacteria, and yeast, respiration is inhibited when high concentrations of glucose are added to the culture medium. This phenomenon has been named the "Crabtree effect." We used yeast to investigate (i) the short term event(s) asso...

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