Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats

Systemic ethanol administration increases neuroactive steroid levels that increase ethanol sensitivity. Acetaldehyde is a biologically active compound that may contribute to behavioral and rewarding effects of ethanol. We investigated the role of acetaldehyde in ethanol-induced elevations of 3alpha-...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2008-10, Vol.32 (10), p.1774
Hauptverfasser:	Boyd, Kevin N, O'Buckley, Todd K, Morrow, A Leslie
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaldehyde - blood Acetaldehyde - pharmacology Animals Cerebral Cortex - drug effects Cerebral Cortex - metabolism Cyanamide - pharmacology Ethanol - metabolism Ethanol - pharmacology Male Pregnanolone - metabolism Rats Rats, Sprague-Dawley
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