Ghrelin and orotic acid increased in subclinical mastitis
Abstract Hormone ghrelin and orotic acid accelerate wound healing as well as controlling inflammation and immunity. We have, therefore, investigated the serum and milk levels of ghrelin and orotic acid in dairy cows with (n = 21) or without (n = 21) subclinical mastitis. Acylated and des-acylated gh...
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| Veröffentlicht in: | Archives of physiology and biochemistry 2008-07, Vol.114 (3), p.178-182 |
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| container_title | Archives of physiology and biochemistry |
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| creator | Karatas, F. Aydin, S. Kaygusuzoglu, E. Yildiz, H. Erulas, F. A. Ozkan, Y. |
| description | Abstract
Hormone ghrelin and orotic acid accelerate wound healing as well as controlling inflammation and immunity. We have, therefore, investigated the serum and milk levels of ghrelin and orotic acid in dairy cows with (n = 21) or without (n = 21) subclinical mastitis. Acylated and des-acylated ghrelin as well as orotic acid concentration were detected by using high performance liquid chromatography (HPLC). The results revealed that ghrelin level in milk and serum was significantly higher in dairy cows with subclinical mastitis than that of dairy cows without subclinical mastitis. This was also the case when the orotic acid concentrations in dairy cows with subclinical mastitis were compared with those dairy cows without subclinical mastitis. In conclusion, ghrelin and orotic acid occur in particularly high concentrations in subclinical mastitis, and might, therefore, be required in greater amounts for tissue repair and may be also used as a indicator for subclinical mastitis. |
| doi_str_mv | 10.1080/13813450802180940 |
| format | Article |
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Hormone ghrelin and orotic acid accelerate wound healing as well as controlling inflammation and immunity. We have, therefore, investigated the serum and milk levels of ghrelin and orotic acid in dairy cows with (n = 21) or without (n = 21) subclinical mastitis. Acylated and des-acylated ghrelin as well as orotic acid concentration were detected by using high performance liquid chromatography (HPLC). The results revealed that ghrelin level in milk and serum was significantly higher in dairy cows with subclinical mastitis than that of dairy cows without subclinical mastitis. This was also the case when the orotic acid concentrations in dairy cows with subclinical mastitis were compared with those dairy cows without subclinical mastitis. In conclusion, ghrelin and orotic acid occur in particularly high concentrations in subclinical mastitis, and might, therefore, be required in greater amounts for tissue repair and may be also used as a indicator for subclinical mastitis.</description><identifier>ISSN: 1381-3455</identifier><identifier>EISSN: 1744-4160</identifier><identifier>DOI: 10.1080/13813450802180940</identifier><identifier>PMID: 18629683</identifier><language>eng</language><publisher>Basingstoke: Informa UK Ltd</publisher><subject>Animals ; Biological and medical sciences ; Cattle ; Chromatography, High Pressure Liquid ; cow milk ; Dairying ; Female ; Fundamental and applied biological sciences. Psychology ; Ghrelin ; Ghrelin - blood ; Ghrelin - metabolism ; Mastitis - metabolism ; Milk - metabolism ; orotic acid ; Orotic Acid - blood ; Orotic Acid - metabolism ; subclinical mastitis ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>Archives of physiology and biochemistry, 2008-07, Vol.114 (3), p.178-182</ispartof><rights>2008 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2008</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-9a98712bf9833c8b97be39abe06e051c3120e1617afd4a3df1ab59148a00a4fd3</citedby><cites>FETCH-LOGICAL-c349t-9a98712bf9833c8b97be39abe06e051c3120e1617afd4a3df1ab59148a00a4fd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/13813450802180940$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/13813450802180940$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20554028$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18629683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Karatas, F.</creatorcontrib><creatorcontrib>Aydin, S.</creatorcontrib><creatorcontrib>Kaygusuzoglu, E.</creatorcontrib><creatorcontrib>Yildiz, H.</creatorcontrib><creatorcontrib>Erulas, F. A.</creatorcontrib><creatorcontrib>Ozkan, Y.</creatorcontrib><title>Ghrelin and orotic acid increased in subclinical mastitis</title><title>Archives of physiology and biochemistry</title><addtitle>Arch Physiol Biochem</addtitle><description>Abstract
Hormone ghrelin and orotic acid accelerate wound healing as well as controlling inflammation and immunity. We have, therefore, investigated the serum and milk levels of ghrelin and orotic acid in dairy cows with (n = 21) or without (n = 21) subclinical mastitis. Acylated and des-acylated ghrelin as well as orotic acid concentration were detected by using high performance liquid chromatography (HPLC). The results revealed that ghrelin level in milk and serum was significantly higher in dairy cows with subclinical mastitis than that of dairy cows without subclinical mastitis. This was also the case when the orotic acid concentrations in dairy cows with subclinical mastitis were compared with those dairy cows without subclinical mastitis. In conclusion, ghrelin and orotic acid occur in particularly high concentrations in subclinical mastitis, and might, therefore, be required in greater amounts for tissue repair and may be also used as a indicator for subclinical mastitis.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cattle</subject><subject>Chromatography, High Pressure Liquid</subject><subject>cow milk</subject><subject>Dairying</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Ghrelin</subject><subject>Ghrelin - blood</subject><subject>Ghrelin - metabolism</subject><subject>Mastitis - metabolism</subject><subject>Milk - metabolism</subject><subject>orotic acid</subject><subject>Orotic Acid - blood</subject><subject>Orotic Acid - metabolism</subject><subject>subclinical mastitis</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>1381-3455</issn><issn>1744-4160</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9LxDAQxYMouq5-AC_Si96qM03aTdCLiP9gwYueyzRN2Sxto0mL-O3Nsqsiwp7mwfzeMO8xdoJwgSDhErlELvIoM5SgBOywCc6ESAUWsBt13KcRyA_YYQhLAMykwn12gLLIVCH5hKmHhTet7RPq68R5N1idkLZ1YnvtDQWzUkkYKx0hq6lNOgqDHWw4YnsNtcEcb-aUvd7fvdw-pvPnh6fbm3mquVBDqkjJGWZVoyTnWlZqVhmuqDJQGMhRc8zAYIEzampBvG6QqlyhkARAoqn5lJ2v77559z6aMJSdDdq0LfXGjaEsFAeFkEcQ16D2LgRvmvLN2478Z4lQrvoq__UVPaeb42PVmfrXsSkoAmcbgEJM33jqtQ0_XAZ5LiCTkbtec7ZvnO_ow_m2Lgf6bJ3_NvFtf1z9sS8MtcNCkzfl0o2-jwVvSfEFV0eWlg</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>Karatas, F.</creator><creator>Aydin, S.</creator><creator>Kaygusuzoglu, E.</creator><creator>Yildiz, H.</creator><creator>Erulas, F. A.</creator><creator>Ozkan, Y.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>Ghrelin and orotic acid increased in subclinical mastitis</title><author>Karatas, F. ; Aydin, S. ; Kaygusuzoglu, E. ; Yildiz, H. ; Erulas, F. A. ; Ozkan, Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-9a98712bf9833c8b97be39abe06e051c3120e1617afd4a3df1ab59148a00a4fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cattle</topic><topic>Chromatography, High Pressure Liquid</topic><topic>cow milk</topic><topic>Dairying</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Ghrelin</topic><topic>Ghrelin - blood</topic><topic>Ghrelin - metabolism</topic><topic>Mastitis - metabolism</topic><topic>Milk - metabolism</topic><topic>orotic acid</topic><topic>Orotic Acid - blood</topic><topic>Orotic Acid - metabolism</topic><topic>subclinical mastitis</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karatas, F.</creatorcontrib><creatorcontrib>Aydin, S.</creatorcontrib><creatorcontrib>Kaygusuzoglu, E.</creatorcontrib><creatorcontrib>Yildiz, H.</creatorcontrib><creatorcontrib>Erulas, F. A.</creatorcontrib><creatorcontrib>Ozkan, Y.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of physiology and biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karatas, F.</au><au>Aydin, S.</au><au>Kaygusuzoglu, E.</au><au>Yildiz, H.</au><au>Erulas, F. A.</au><au>Ozkan, Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ghrelin and orotic acid increased in subclinical mastitis</atitle><jtitle>Archives of physiology and biochemistry</jtitle><addtitle>Arch Physiol Biochem</addtitle><date>2008-07</date><risdate>2008</risdate><volume>114</volume><issue>3</issue><spage>178</spage><epage>182</epage><pages>178-182</pages><issn>1381-3455</issn><eissn>1744-4160</eissn><abstract>Abstract
Hormone ghrelin and orotic acid accelerate wound healing as well as controlling inflammation and immunity. We have, therefore, investigated the serum and milk levels of ghrelin and orotic acid in dairy cows with (n = 21) or without (n = 21) subclinical mastitis. Acylated and des-acylated ghrelin as well as orotic acid concentration were detected by using high performance liquid chromatography (HPLC). The results revealed that ghrelin level in milk and serum was significantly higher in dairy cows with subclinical mastitis than that of dairy cows without subclinical mastitis. This was also the case when the orotic acid concentrations in dairy cows with subclinical mastitis were compared with those dairy cows without subclinical mastitis. In conclusion, ghrelin and orotic acid occur in particularly high concentrations in subclinical mastitis, and might, therefore, be required in greater amounts for tissue repair and may be also used as a indicator for subclinical mastitis.</abstract><cop>Basingstoke</cop><pub>Informa UK Ltd</pub><pmid>18629683</pmid><doi>10.1080/13813450802180940</doi><tpages>5</tpages></addata></record> |
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| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Animals Biological and medical sciences Cattle Chromatography, High Pressure Liquid cow milk Dairying Female Fundamental and applied biological sciences. Psychology Ghrelin Ghrelin - blood Ghrelin - metabolism Mastitis - metabolism Milk - metabolism orotic acid Orotic Acid - blood Orotic Acid - metabolism subclinical mastitis Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Ghrelin and orotic acid increased in subclinical mastitis |
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